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Journal of Medicinal Chemistry
|
June 24, 2011
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential
Jose M Coteron, María Marco, Jorge Esquivias, et al.
Journal of Medicinal Chemistry
|
April 30, 2016
Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity
Sreekanth Kokkonda, Xiaoyi Deng, Karen L White, et al.
Nature
|
May 21, 2025
In vivo screen of Plasmodium targets for mosquito-based malaria control
Alexandra S Probst, Douglas G Paton, Federico Appetecchia, et al.
Journal of Medicinal Chemistry
|
April 7, 2020
Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria
Sreekanth Kokkonda, Xiaoyi Deng, Karen L White, et al.
ACS Infectious Diseases
|
September 20, 2016
A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria
Margaret A Phillips, Karen L White, Sreekanth Kokkonda, et al.
ACS Infectious Diseases
|
November 11, 2024
Tambjamines as Fast-Acting Multistage Antimalarials
Amrendra Kumar, Yuexin Li, Rozalia A Dodean, et al.
Science Translational Medicine
|
March 22, 2013
Quinolone-3-diarylethers: a new class of antimalarial drug
Aaron Nilsen, Alexis N LaCrue, Karen L White, et al.
Journal of Medicinal Chemistry
|
October 10, 2022
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of <b>UCB7362</b>
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, et al.
Journal of Medicinal Chemistry
|
April 20, 2021
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
Michael J Palmer, Xiaoyi Deng, Shawn Watts, et al.
Science Translational Medicine
|
July 17, 2015
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
Margaret A Phillips, Julie Lotharius, Kennan Marsh, et al.
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of 9
Search research articles
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Showing results (71-80 of 82) with videos related to
Sort By:
Page
of 9
Journal of Medicinal Chemistry
|
June 24, 2011
Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential
Jose M Coteron, María Marco, Jorge Esquivias, et al.
Journal of Medicinal Chemistry
|
April 30, 2016
Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity
Sreekanth Kokkonda, Xiaoyi Deng, Karen L White, et al.
Nature
|
May 21, 2025
In vivo screen of Plasmodium targets for mosquito-based malaria control
Alexandra S Probst, Douglas G Paton, Federico Appetecchia, et al.
Journal of Medicinal Chemistry
|
April 7, 2020
Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria
Sreekanth Kokkonda, Xiaoyi Deng, Karen L White, et al.
ACS Infectious Diseases
|
September 20, 2016
A Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitor with Improved Drug-like Properties for Treatment and Prevention of Malaria
Margaret A Phillips, Karen L White, Sreekanth Kokkonda, et al.
ACS Infectious Diseases
|
November 11, 2024
Tambjamines as Fast-Acting Multistage Antimalarials
Amrendra Kumar, Yuexin Li, Rozalia A Dodean, et al.
Science Translational Medicine
|
March 22, 2013
Quinolone-3-diarylethers: a new class of antimalarial drug
Aaron Nilsen, Alexis N LaCrue, Karen L White, et al.
Journal of Medicinal Chemistry
|
October 10, 2022
Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of <b>UCB7362</b>
Martin A Lowe, Alvaro Cardenas, Jean-Pierre Valentin, et al.
Journal of Medicinal Chemistry
|
April 20, 2021
Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series
Michael J Palmer, Xiaoyi Deng, Shawn Watts, et al.
Science Translational Medicine
|
July 17, 2015
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
Margaret A Phillips, Julie Lotharius, Kennan Marsh, et al.
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of 9