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Chemmedchem
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April 27, 2011
Design strategies for bivalent ligands targeting GPCRs
Jeremy Shonberg, Peter J Scammells, Ben Capuano
Bioorganic & Medicinal Chemistry
|
February 2, 2015
GPCR crystal structures: Medicinal chemistry in the pocket
Jeremy Shonberg, Ralf C Kling, Peter Gmeiner, et al.
Journal of Medicinal Chemistry
|
May 11, 2017
Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased D<sub>2</sub>R Agonists
Barbara Männel, Daniela Dengler, Jeremy Shonberg, et al.
Medicinal Research Reviews
|
May 7, 2014
Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective
Jeremy Shonberg, Laura Lopez, Peter J Scammells, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2013
Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space
Manuela Jörg, Jeremy Shonberg, Frankie S Mak, et al.
Journal of Medicinal Chemistry
|
October 22, 2013
A structure-activity analysis of biased agonism at the dopamine D2 receptor
Jeremy Shonberg, Carmen Klein Herenbrink, Laura López, et al.
Journal of Medicinal Chemistry
|
June 9, 2015
Structure-activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor
Jeremy Shonberg, Christopher Draper-Joyce, Shailesh N Mistry, et al.
Journal of Medicinal Chemistry
|
August 11, 2015
Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand
Shailesh N Mistry, Jeremy Shonberg, Christopher J Draper-Joyce, et al.
ACS Chemical Biology
|
July 25, 2019
Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, et al.
Nature Communications
|
April 14, 2023
Constrained catecholamines gain β<sub>2</sub>AR selectivity through allosteric effects on pocket dynamics
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, et al.
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Search research articles
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Showing results (1-10 of 16) with videos related to
Sort By:
Page
of 2
Chemmedchem
|
April 27, 2011
Design strategies for bivalent ligands targeting GPCRs
Jeremy Shonberg, Peter J Scammells, Ben Capuano
Bioorganic & Medicinal Chemistry
|
February 2, 2015
GPCR crystal structures: Medicinal chemistry in the pocket
Jeremy Shonberg, Ralf C Kling, Peter Gmeiner, et al.
Journal of Medicinal Chemistry
|
May 11, 2017
Hydroxy-Substituted Heteroarylpiperazines: Novel Scaffolds for β-Arrestin-Biased D<sub>2</sub>R Agonists
Barbara Männel, Daniela Dengler, Jeremy Shonberg, et al.
Medicinal Research Reviews
|
May 7, 2014
Biased agonism at G protein-coupled receptors: the promise and the challenges--a medicinal chemistry perspective
Jeremy Shonberg, Laura Lopez, Peter J Scammells, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 23, 2013
Novel adenosine A(2A) receptor ligands: a synthetic, functional and computational investigation of selected literature adenosine A(2A) receptor antagonists for extending into extracellular space
Manuela Jörg, Jeremy Shonberg, Frankie S Mak, et al.
Journal of Medicinal Chemistry
|
October 22, 2013
A structure-activity analysis of biased agonism at the dopamine D2 receptor
Jeremy Shonberg, Carmen Klein Herenbrink, Laura López, et al.
Journal of Medicinal Chemistry
|
June 9, 2015
Structure-activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor
Jeremy Shonberg, Christopher Draper-Joyce, Shailesh N Mistry, et al.
Journal of Medicinal Chemistry
|
August 11, 2015
Discovery of a Novel Class of Negative Allosteric Modulator of the Dopamine D2 Receptor Through Fragmentation of a Bitopic Ligand
Shailesh N Mistry, Jeremy Shonberg, Christopher J Draper-Joyce, et al.
ACS Chemical Biology
|
July 25, 2019
Molecular Determinants of the Intrinsic Efficacy of the Antipsychotic Aripiprazole
Carmen Klein Herenbrink, Ravi Verma, Herman D Lim, et al.
Nature Communications
|
April 14, 2023
Constrained catecholamines gain β<sub>2</sub>AR selectivity through allosteric effects on pocket dynamics
Xinyu Xu, Jeremy Shonberg, Jonas Kaindl, et al.
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of 2