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Expert Opinion on Therapeutic Patents|May 20, 2011
Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent reviewArie Zask, Jeroen C Verheijen, David J Richard
Current Opinion in Drug Discovery & Development|July 3, 2010
Recent advances in the development of selective, ATP-competitive inhibitors of mTORDavid J Richard, Jeroen C Verheijen, Arie Zask
Pharmaceutical Patent Analyst|December 21, 2013
New antibacterial agents: patent applications published in 2011Thomas A Keating, Troy Lister, Jeroen C Verheijen
Pharmaceutical Patent Analyst|November 19, 2013
New antibacterial agents: patent applications published in 2010Suzanne S Stokes, Marshall Morningstar, Helena Kocis, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3KalphaDavid J Richard, Jeroen C Verheijen, Ker Yu, et al.
Bioorganic & Medicinal Chemistry Letters|November 10, 2009
Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3KJeroen C Verheijen, Ker Yu, Lourdes Toral-Barza, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stabilityJeroen C Verheijen, David J Richard, Kevin Curran, et al.
Bioorganic & Medicinal Chemistry Letters|December 8, 2009
Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR)Joshua Kaplan, Jeroen C Verheijen, Natasja Brooijmans, et al.
Bioorganic & Medicinal Chemistry Letters|March 16, 2010
Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitorsArie Zask, Jeroen C Verheijen, David J Richard, et al.
Bioorganic & Medicinal Chemistry Letters|November 10, 2009
Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: discovery of highly potent and selective analogs with improved human microsomal stabilityDavid J Richard, Jeroen C Verheijen, Kevin Curran, et al.
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