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Trends in Pharmacological Sciences|March 19, 2021
Efflux Limits Tumor Drug Delivery Despite Disrupted BBBJessica I Griffith, Jann N Sarkaria, William F ElmquistPharmaceutics|December 16, 2020
Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain TumorsJessica I Griffith, Sneha Rathi, Wenqiu Zhang, et al.Journal of Internal Medicine|January 18, 2022
The influence of the blood-brain barrier in the treatment of brain tumoursSneha Rathi, Jessica I Griffith, Wenjuan Zhang, et al.Pharmacological Research|June 22, 2017
Drug delivery to melanoma brain metastases: Can current challenges lead to new opportunities?Gautham Gampa, Shruthi Vaidhyanathan, Jann N Sarkaria, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 31, 2014
Factors influencing the CNS distribution of a novel MEK-1/2 inhibitor: implications for combination therapy for melanoma brain metastasesShruthi Vaidhyanathan, Rajendar K Mittapalli, Jann N Sarkaria, et al.The Journal of Pharmacology and Experimental Therapeutics|February 15, 2018
Pharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain BarrierJanice K Laramy, Minjee Kim, Karen E Parrish, et al.The Journal of Pharmacology and Experimental Therapeutics|September 11, 2015
Efflux transporters at the blood-brain barrier limit delivery and efficacy of cyclin-dependent kinase 4/6 inhibitor palbociclib (PD-0332991) in an orthotopic brain tumor modelKaren E Parrish, Jenny Pokorny, Rajendar K Mittapalli, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 18, 2019
Brain Distributional Kinetics of a Novel MDM2 Inhibitor SAR405838: Implications for Use in Brain Tumor TherapyMinjee Kim, Janice K Laramy, Gautham Gampa, et al.Neuro-Oncology|September 12, 2015
Strategies to improve delivery of anticancer drugs across the blood-brain barrier to treat glioblastomaRajneet K Oberoi, Karen E Parrish, Terence T Sio, et al.The Journal of Pharmacology and Experimental Therapeutics|September 22, 2022
Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain TumorsSurabhi Talele, Wenjuan Zhang, Jiajia Chen, et al.Pageof 35