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Journal of Medicinal Chemistry|March 28, 2020
How We Think about Targeting RNA with Small MoleculesMatthew G Costales, Jessica L Childs-Disney, Hafeez S Haniff, et al.
Nucleic Acids Research|July 15, 2009
Improvement of RNA secondary structure prediction using RNase H cleavage and randomized oligonucleotidesAndrew D Kauffmann, Ryan J Campagna, Chantal B Bartels, et al.
ACS Chemical Biology|November 8, 2012
Rational design of bioactive, modularly assembled aminoglycosides targeting the RNA that causes myotonic dystrophy type 1Jessica L Childs-Disney, Raman Parkesh, Masayuki Nakamori, et al.
Nucleic Acids Research|May 22, 2023
Conformational dynamics of RNA G4C2 and G2C4 repeat expansions causing ALS/FTD using NMR and molecular dynamics studiesAmirhossein Taghavi, Jared T Baisden, Jessica L Childs-Disney, et al.
Methods in Enzymology|June 27, 2019
Identifying and validating small molecules interacting with RNA (SMIRNAs)Matthew D Disney, Sai Pradeep Velagapudi, Yue Li, et al.
ACS Chemical Biology|February 16, 2012
Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactiveJessica L Childs-Disney, Jason Hoskins, Suzanne G Rzuczek, et al.
ACS Chemical Biology|February 11, 2014
Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotidesTuan Tran, Jessica L Childs-Disney, Biao Liu, et al.
ACS Chemical Biology|January 19, 2012
Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcriptsAmit Kumar, Raman Parkesh, Lukasz J Sznajder, et al.
ACS Chemical Biology|October 12, 2023
Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular SelectivityBlessy M Suresh, Yuquan Tong, Daniel Abegg, et al.
Plos One|July 11, 2019
The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biologyJonathan L Chen, Walter N Moss, Adam Spencer, et al.
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