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Journal of the American Chemical Society|June 23, 2022
Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader ofYuquan Tong, Quentin M R Gibaut, Warren Rouse, et al.Proceedings of the National Academy of Sciences of the United States of America|February 3, 2022
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitorRaphael I Benhamou, Blessy M Suresh, Yuquan Tong, et al.Chem|February 6, 2019
A Massively Parallel Selection of Small Molecule-RNA Motif Binding Partners Informs Design of an Antiviral from SequenceJessica L Childs-Disney, Tuan Tran, Balayeshwanth R Vummidi, et al.Cell Chemical Biology|September 26, 2018
Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAsSai Pradeep Velagapudi, Matthew G Costales, Balayeshwanth R Vummidi, et al.Journal of the American Chemical Society|August 13, 2021
Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease RecruitmentPeiyuan Zhang, Xiaohui Liu, Daniel Abegg, et al.Proceedings of the National Academy of Sciences of the United States of America|January 23, 2020
Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancerMatthew G Costales, Haruo Aikawa, Yue Li, et al.Proceedings of the National Academy of Sciences of the United States of America|January 5, 2024
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimeraYuquan Tong, Peiyuan Zhang, Xueyi Yang, et al.Proceedings of the National Academy of Sciences of the United States of America|January 5, 2020
Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNAPeiyuan Zhang, Hye-Jin Park, Jie Zhang, et al.Cell Chemical Biology|December 4, 2018
The Hairpin Form of r(G4C2)exp in c9ALS/FTD Is Repeat-Associated Non-ATG Translated and a Target for Bioactive Small MoleculesZi-Fu Wang, Andrei Ursu, Jessica L Childs-Disney, et al.Nature Communications|June 29, 2013
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small moleculesJessica L Childs-Disney, Ewa Stepniak-Konieczna, Tuan Tran, et al.Pageof 9