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Chemmedchem|February 16, 2026
Small Molecule Kinase Inhibitors with In Vitro β-Hematin Formation and Plasmodium falciparum Protein Kinase G Inhibitory Activity Identified Using Machine LearningJessica L Thibaud, Nicolaas Salomane, Sarah Harries, et al.Chemmedchem|February 16, 2026
Exploration of Antiplasmodium Chemical Space Identifies New Inhibitors of β-Hematin Formation from Areas of EnrichmentJessica L Thibaud, Dirkie C Myburgh, Rebecca D Sandlin, et al.Journal of Medicinal Chemistry|September 8, 2025
Structure-Activity Relationships of 3-Hydroxypropanamidines (HPAs) with Potent In Vivo Antimalarial ActivitySaskia Klein, Alena Moritz, Lais Pessanha de Carvalho, et al.ACS Infectious Diseases|March 31, 2026
Protein Arginine Methyltransferase Inhibitors Target Multiple Stages of Plasmodium falciparum Parasites In VitroDaniel Opperman, Tayla Rabie, Marché Maré, et al.Journal of Medicinal Chemistry|December 26, 2024
TKK130 is a 3-Hydroxy-Propanamidine (HPA) with Potent Antimalarial In Vivo Activity and a High Barrier to ResistanceTanja C Knaab, Alena Moritz, Lais Pessanha de Carvalho, et al.Angewandte Chemie (International Ed. in English)|October 24, 2025
Targeting Aurora Kinases as Essential Cell-Cycle Regulators to Deliver Multi-Stage Antimalarials Against Plasmodium FalciparumHenrico Langeveld, Keletso Maepa, Marché Maree, et al.Pageof 1