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Trends in Biochemical Sciences|April 21, 2021
Histone PTM Crosstalk Stimulates Dot1 Methyltransferase ActivityJevon A Cutler, Florian Perner, Scott A Armstrong
Cells|December 29, 2020
Targeting Chromatin Complexes in Myeloid Malignancies and Beyond: From Basic Mechanisms to Clinical InnovationFlorian Perner, Scott A Armstrong
International Journal of Cancer|January 31, 2025
Targeting the Menin-KMT2A interaction in leukemia: Lessons learned and future directionsFlorian Perner, Jayant Y Gadrey, Scott A Armstrong, et al.
Nature Communications|May 8, 2026
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trialsWallace Bourgeois, Hannah E Rice, Daniela V Wenge, et al.
Blood|June 29, 2026
Menin-MLL inhibitors enhance JUND activity in MLLr leukemic cells contributing to tumorigenesis and therapy resistanceEzgi Ozyerli-Goknar, Sheikh Nizamuddin, Viktor Fetsch, et al.
Cancer Discovery|May 2, 2022
MOZ and Menin-MLL Complexes Are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal TumorMatthew L Hemming, Morgan R Benson, Michael A Loycano, et al.
Molecular Cell|March 4, 2022
MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscapeSarah Naomi Olsen, Laura Godfrey, James P Healy, et al.
Cell Reports|October 30, 2024
NUP98 fusion proteins and KMT2A-MENIN antagonize PRC1.1 to drive gene expression in AMLEmily B Heikamp, Cynthia Martucci, Jill A Henrich, et al.
Molecular & Cellular Oncology|April 15, 2021
A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNsTina M Schnoeder, Florian Perner, Florian H Heidel
Nature Cancer|May 9, 2022
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemiaBrandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, et al.
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