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Nature Communications|May 8, 2026
CRISPR base editor screening identifies spectrum of MEN1 mutations impacting menin inhibitors in clinical trialsWallace Bourgeois, Hannah E Rice, Daniela V Wenge, et al.Nature Cancer|May 9, 2022
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemiaBrandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, et al.Blood|December 14, 2023
Mezigdomide is effective alone and in combination with menin inhibition in preclinical models of KMT2A-r and NPM1c AMLWallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, et al.Nature|March 16, 2023
MEN1 mutations mediate clinical resistance to menin inhibitionFlorian Perner, Eytan M Stein, Daniela V Wenge, et al.Molecular Cell|July 21, 2023
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stabilityJonathan M Tsai, Jacob D Aguirre, Yen-Der Li, et al.Blood|June 21, 2024
Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemiasMin Chul Kwon, Jan Willem Thuring, Olivier Querolle, et al.Leukemia & Lymphoma|August 25, 2012
Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working GroupArjan A van de Loosdrecht, Robin Ireland, Wolfgang Kern, et al.Pageof 2