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Journal of Medicinal Chemistry|July 23, 2020
Design, Synthesis, and Evaluation of New Quinazolinone Derivatives that Inhibit Bloom Syndrome Protein (BLM) Helicase, Trigger DNA Damage at the Telomere Region, and Synergize with PARP InhibitorsChen-Xi Wang, Zi-Lin Zhang, Qi-Kun Yin, et al.Cell Chemical Biology|October 4, 2016
Conformation Selective Antibody Enables Genome Profiling and Leads to Discovery of Parallel G-Quadruplex in Human TelomeresHui-Yun Liu, Qi Zhao, Tian-Peng Zhang, et al.Journal of Medicinal Chemistry|June 13, 2017
New Disubstituted Quindoline Derivatives Inhibiting Burkitt's Lymphoma Cell Proliferation by Impeding c-MYC TranscriptionHui-Yun Liu, Ai-Chun Chen, Qi-Kun Yin, et al.Journal of Medicinal Chemistry|May 30, 2023
Design and Synthesis of Bouchardatine Derivatives as a Novel AMP-Activated Protein Kinase Activator for the Treatment of Colorectal CancerYao-Hao Xu, Yu-Tao Hu, Shu-Min Xu, et al.British Journal of Pharmacology|November 16, 2021
A novel HSF1 activator ameliorates non-alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidationYong Rao, Chan Li, Yu-Tao Hu, et al.European Journal of Medicinal Chemistry|March 13, 2020
Discovery of a promising agent IQZ23 for the treatment of obesity and related metabolic disordersYong Rao, Zhao Xu, Yu-Tao Hu, et al.Journal of Medicinal Chemistry|February 13, 2026
An Orally Available Telomeric G-Quadruplex Ligand Induces Telomere Crisis and Dual DNA/RNA-Sensing Innate Immunity for Cancer TherapyJiong-Heng Cai, Yao-Hui Shi, Dan-Yan Yang, et al.Pageof 14