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Medicinal Research Reviews|April 1, 2026
Aldo-Keto Reductase Family 1 Member B10 as a Therapeutic Frontier: Advances in Inhibitor Design and Multimodal ApproachesJikuan Shao, Xiaolong Wang, Can Guo, et al.European Journal of Medicinal Chemistry|February 27, 2025
Discovery of highly potent AKR1Cs pan-inhibitors as chemotherapeutic potentiators to restore breast cancer drug resistanceShuaishuai Xing, Yijun Liu, Huanfang Xie, et al.Journal of Medicinal Chemistry|January 30, 2026
Discovery of Highly Selective AKR1C3 Inhibitors to Overcome EGFR C797S-Mediated Osimertinib Resistance in Non-Small Cell Lung CancerCan Guo, Xiaolong Wang, Qianwen Guan, et al.Journal of Medicinal Chemistry|November 22, 2025
Small Molecule-Drug Conjugates: An Emerging Drug Design Strategy for Targeted TherapeuticsXiaolong Wang, Can Guo, Jikuan Shao, et al.Bioorganic & Medicinal Chemistry|May 18, 2026
PROTACs for central nervous system disorders: challenges and opportunitiesNa Zheng, Jikuan Shao, Baichen Xiong, et al.Journal of Medicinal Chemistry|June 2, 2025
Lead Optimization of a Butyrylcholinesterase Inhibitor for the Treatment of Alzheimer's DiseaseUrban Košak, Nika Strašek Benedik, Damijan Knez, et al.Pageof 1