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Bioorganic & Medicinal Chemistry Letters|January 8, 2011
Sodium [2'-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetate (AM432): a potent, selective prostaglandin D2 receptor antagonistNicholas Stock, Deborah Volkots, Karin Stebbins, et al.Bioorganic & Medicinal Chemistry Letters|July 18, 2009
Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine model of allergic rhinitisBrian A Stearns, Christopher Baccei, Gretchen Bain, et al.Journal of Medicinal Chemistry|November 9, 2011
5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitorNicholas S Stock, Gretchen Bain, Jasmine Zunic, et al.Journal of Medicinal Chemistry|May 5, 2017
Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2)Martin W Rowbottom, Gretchen Bain, Imelda Calderon, et al.The Journal of Pharmacology and Experimental Therapeutics|December 10, 2009
Pharmacological blockade of the DP2 receptor inhibits cigarette smoke-induced inflammation, mucus cell metaplasia, and epithelial hyperplasia in the mouse lungKarin J Stebbins, Alex R Broadhead, Christopher S Baccei, et al.European Journal of Pharmacology|June 4, 2010
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammationDaniel S Lorrain, Gretchen Bain, Lucia D Correa, et al.Nature Communications|November 7, 2020
mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function declineKseniya Obraztsova, Maria C Basil, Ryan Rue, et al.Pageof 5