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Journal of Medicinal Chemistry|August 20, 2016
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance ProfilesDongwei Kang, Zengjun Fang, Zhenyu Li, et al.Bioorganic & Medicinal Chemistry|February 26, 2025
Optimizing biofilm inhibitors: Balancing activity and toxicity in 2N-aminated 5-aryl-2-aminoimidazolesLynn Maetens, Banibrata Maiti, Freya Cools, et al.Biochemical Pharmacology|July 25, 2024
Tankyrase1/2 inhibitor XAV-939 reverts EMT and suggests that PARylation partially regulates aerobic activities in human hepatocytes and HepG2 cellsKristof De Vos, Adamantios Mavrogiannis, Justina Clarinda Wolters, et al.Virology|May 15, 2007
Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanionsClaire Bertaux, Dirk Daelemans, Laurent Meertens, et al.The Journal of Clinical Investigation|October 20, 2007
Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voidingThomas Gevaert, Joris Vriens, Andrei Segal, et al.Nature Communications|February 7, 2018
Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genesJasper Edgar Neggers, Bert Kwanten, Tim Dierckx, et al.Nature Communications|July 20, 2019
Bypassing pan-enterovirus host factor PLA2G16Jim Baggen, Yue Liu, Heyrhyoung Lyoo, et al.Chemical Biology & Drug Design|August 7, 2018
Design, synthesis, and antiviral evaluation of novel hydrazone-substituted thiophene[3,2-d]pyrimidine derivatives as potent human immunodeficiency virus-1 inhibitorsZhao Wang, Dongwei Kang, Meng Chen, et al.Oncotarget|November 20, 2018
Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progressionAmro Aboukameel, Irfana Muqbil, Erkan Baloglu, et al.ACS Medicinal Chemistry Letters|April 20, 2018
Discovery of Novel Diarylpyrimidine Derivatives as Potent HIV-1 NNRTIs Targeting the "NNRTI Adjacent" Binding SiteZhipeng Huo, Heng Zhang, Dongwei Kang, et al.Pageof 20