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European Journal of Medicinal Chemistry|August 25, 2020
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitorsPhilippe Gilles, Rudra S Kashyap, Maria João Freitas, et al.Angewandte Chemie (International Ed. in English)|May 23, 2023
Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer AgentsEveline Vriens, Dries De Ruysscher, Angus N M Weir, et al.Cell Reports|March 15, 2016
The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin AInmaculada Segura, Christian Lange, Ellen Knevels, et al.Journal of Medicinal Chemistry|February 6, 2019
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety ProfilesBoshi Huang, Wenmin Chen, Tong Zhao, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 14, 2019
Preclinical Assessment with Clinical Validation of Selinexor with Gemcitabine and Nab-Paclitaxel for the Treatment of Pancreatic Ductal AdenocarcinomaAsfar S Azmi, Husain Yar Khan, Irfana Muqbil, et al.Journal of Medicinal Chemistry|May 9, 2017
Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated VariantsDongwei Kang, Zengjun Fang, Boshi Huang, et al.The Journal of Experimental Medicine|January 28, 2021
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesisAdeline Rosu, Najla El Hachem, Francesca Rapino, et al.Bioorganic & Medicinal Chemistry|February 2, 2015
Scaffold hopping: exploration of acetanilide-containing uracil analogues as potential NNRTIsDenis A Babkov, Vladimir T Valuev-Elliston, Maria P Paramonova, et al.EMBO Reports|September 24, 2019
STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoesAlexandre Pj Martin, Maarten Jacquemyn, Joanna Lipecka, et al.Cell Death Discovery|March 23, 2026
ADA2-deficient cells exhibit increased levels of cell death and metabolic disturbancesLisa Ehlers, Marjon Wouters, Bethany Pillay, et al.Pageof 20