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The AAPS Journal|September 9, 2005
Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time seriesRichard R Almon, Debra C Dubois, Jin Y Jin, et al.
The Journal of Pharmacology and Experimental Therapeutics|June 17, 2003
Modeling of corticosteroid pharmacogenomics in rat liver using gene microarraysJin Y Jin, Richard R Almon, Debra C DuBois, et al.
Biopharmaceutics & Drug Disposition|January 10, 2012
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studiesYuan Chen, Jin Y Jin, Sophie Mukadam, et al.
The Journal of Endocrinology|January 12, 2005
Temporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscleRichard R Almon, Debra C Dubois, Jin Y Jin, et al.
Drugs in R&D|May 3, 2024
Retrospective Assessment of Translational Pharmacokinetic-Pharmacodynamic Modeling Performance: A Case Study with Apitolisib, a Dual PI3K/mTOR InhibitorAnita Moein, Jin Y Jin, Matthew R Wright, et al.
CPT: Pharmacometrics & Systems Pharmacology|October 25, 2023
Comparison of two-stage and joint TGI-OS modeling using data from six atezolizumab clinical studies in patients with metastatic non-small cell lung cancerAntonio Gonçalves, Mathilde Marchand, Phyllis Chan, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 6, 2020
Application of Machine Learning for Tumor Growth Inhibition - Overall Survival Modeling PlatformPhyllis Chan, Xiaofei Zhou, Nina Wang, et al.
Biopharmaceutics & Drug Disposition|December 11, 2012
A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancerSravanthi Cheeti, Nageshwar R Budha, Sharmila Rajan, et al.
CPT: Pharmacometrics & Systems Pharmacology|March 11, 2024
Deep-NCA: A deep learning methodology for performing noncompartmental analysis of pharmacokinetic dataGengbo Liu, Logan Brooks, John Canty, et al.
The AAPS Journal|September 3, 2020
A Physiologically Based Pharmacokinetic Model of Vismodegib: Deconvoluting the Impact of Saturable Plasma Protein Binding, pH-Dependent Solubility and Nonsink PermeationMichael J Dolton, Po-Chang Chiang, Fang Ma, et al.
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