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ACS Medicinal Chemistry Letters
|
May 20, 2026
Discovery of Potent 1,3-Cyclobutane-Containing Dual A<sub>2A</sub>/A<sub>2B</sub> Receptor Antagonists with Low Projected Human Dose for the Treatment of Cancer
Zachary G Brill, Alec H Christian, Lorena Rico, et al.
Signal Transduction and Targeted Therapy
|
February 2, 2026
Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis
Li Li, Ramon Lopez Perez, Khuram Shehzad, et al.
ACS Infectious Diseases
|
April 6, 2024
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, et al.
Journal of Medicinal Chemistry
|
March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor
Mihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
Nature Medicine
|
January 13, 2026
Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis
Brendan M Crowley, Helena I Boshoff, Aidan Boving, et al.
Journal of Medicinal Chemistry
|
September 4, 2024
Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors
Kaitlyn M Logan, Will Kaplan, Vladimir Simov, et al.
Journal of Medicinal Chemistry
|
December 30, 2021
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
Mitchell H Keylor, Anmol Gulati, Solomon D Kattar, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates
Mihirbaran Mandal, Li Xiao, Weidong Pan, et al.
Journal of Medicinal Chemistry
|
February 22, 2024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration
Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
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Showing results (1461-1470 of 1,472) with videos related to
Sort By:
Page
of 148
ACS Medicinal Chemistry Letters
|
May 20, 2026
Discovery of Potent 1,3-Cyclobutane-Containing Dual A<sub>2A</sub>/A<sub>2B</sub> Receptor Antagonists with Low Projected Human Dose for the Treatment of Cancer
Zachary G Brill, Alec H Christian, Lorena Rico, et al.
Signal Transduction and Targeted Therapy
|
February 2, 2026
Wnt-associated DKK3 in keratinocytes mediates radiation-induced hyperplasia, dermatitis and skin fibrosis
Li Li, Ramon Lopez Perez, Khuram Shehzad, et al.
ACS Infectious Diseases
|
April 6, 2024
Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities
Helena I M Boshoff, Katherine Young, Yong-Mo Ahn, et al.
Journal of Medicinal Chemistry
|
March 22, 2017
Can We Make Small Molecules Lean? Optimization of a Highly Lipophilic TarO Inhibitor
Mihirbaran Mandal, Zheng Tan, Christina Madsen-Duggan, et al.
Nature Medicine
|
January 13, 2026
Discovery and development of a new oxazolidinone with reduced toxicity for the treatment of tuberculosis
Brendan M Crowley, Helena I Boshoff, Aidan Boving, et al.
Journal of Medicinal Chemistry
|
September 4, 2024
Discovery and Optimization of N-Heteroaryl Indazole LRRK2 Inhibitors
Kaitlyn M Logan, Will Kaplan, Vladimir Simov, et al.
Journal of Medicinal Chemistry
|
December 30, 2021
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors
Mitchell H Keylor, Anmol Gulati, Solomon D Kattar, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Rapid Evolution of a Fragment-like Molecule to Pan-Metallo-Beta-Lactamase Inhibitors: Initial Leads toward Clinical Candidates
Mihirbaran Mandal, Li Xiao, Weidong Pan, et al.
Journal of Medicinal Chemistry
|
February 22, 2024
Structure Guided Discovery of Novel Pan Metallo-β-Lactamase Inhibitors with Improved Gram-Negative Bacterial Cell Penetration
Shuzhi Dong, Zhiqiang Zhao, Haiqun Tang, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
Page
of 148