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JACS Au|January 30, 2026
PSMA-Targeting Chimeras for Cell-Type-Specific Degradation of Surface Immune Checkpoint Protein PD-L1Yuqing Luo, Xiaoxiao Gong, Keren Peng, et al.European Journal of Medicinal Chemistry|November 27, 2024
Discovery of a potent PARP1 PROTAC as a chemosensitizer for the treatment of colorectal cancerMingfei Wu, Yiming Jiang, Daoming Zhang, et al.Journal of Medicinal Chemistry|July 12, 2024
Discovery of New Phenyltetrazolium Derivatives as Ferroptosis Inhibitors for Treating Ischemic Stroke: An Example Development from Free Radical ScavengersYang Lu, Zexu Shen, Yaping Xu, et al.Journal of Medicinal Chemistry|July 31, 2024
Discovery of an Exceptionally Orally Bioavailable and Potent HPK1 PROTAC with Enhancement of Antitumor Efficacy of Anti-PD-L1 TherapyMingfei Wu, Yiquan Wu, Yuyuan Jin, et al.Journal of Medicinal Chemistry|August 10, 2021
Discovery of <i>N</i>-((3<i>S</i>,4<i>S</i>)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1<i>H</i>-pyrazol-5-yl)benzamide (Hu7691), a Potent and Selective Akt Inhibitor That Enables Decrease of Cutaneous ToxicityJinxin Che, Xiaoyang Dai, Jian Gao, et al.Advanced Science (Weinheim, Baden-Wurttemberg, Germany)|January 25, 2024
Rational Identification of Novel Antibody-Drug Conjugate with High Bystander Killing Effect against Heterogeneous TumorsYu Guo, Zheyuan Shen, Wenbin Zhao, et al.Journal of Medicinal Chemistry|January 17, 2024
Discovery of <i>N</i>-(1-(6-Oxo-1,6-dihydropyrimidine)-pyrazole) Acetamide Derivatives as Novel Noncovalent DprE1 Inhibitors against <i>Mycobacterium tuberculosis</i>Liu Yang, Xueping Hu, Yang Lu, et al.Journal of Medicinal Chemistry|June 7, 2022
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of LymphomaJingyu Zhang, Jinxin Che, Xiaomin Luo, et al.Journal of Medicinal Chemistry|June 24, 2024
Discovery of a Highly Potent and Selective BRD9 PROTAC Degrader Based on E3 Binder Investigation for the Treatment of Hematological TumorsHaiting Duan, Jingyu Zhang, Renzhao Gui, et al.Journal of Medicinal Chemistry|September 30, 2025
Discovery of a Selective and Potent BCL6 PROTAC with Efficacious Antiproliferative Activity for the Treatment of Diffuse Large B-Cell LymphomaXiaoli Yu, Xueyan Liao, Jingyu Zhang, et al.Pageof 10