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Journal of Medicinal Chemistry|July 17, 2020
Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based MethodsDhruba Sarkar, Edward T Olejniczak, Jason Phan, et al.Journal of Cell Science|May 14, 2009
VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxisNicole F Neel, Melanie Barzik, Dayanidhi Raman, et al.Journal of Leukocyte Biology|May 29, 2008
Short tail with skin lesion phenotype occurs in transgenic mice with keratin-14 promoter-directed expression of mutant CXCR2Yingchun Yu, Yingjun Su, Susan R Opalenik, et al.Biophysical Journal|July 21, 2010
Bimodal analysis reveals a general scaling law governing nondirected and chemotactic cell motilityJ Scott Gruver, Alka A Potdar, Junhwan Jeon, et al.ACS Chemical Biology|February 9, 2019
Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular ResponsesDenis T Akan, Jennifer E Howes, Jiqing Sai, et al.Cancer Research|July 28, 2012
INK4a/ARF [corrected] inactivation with activation of the NF-κB/IL-6 pathway is sufficient to drive the development and growth of angiosarcomaJinming Yang, Sara Kantrow, Jiqing Sai, et al.Oncoimmunology|July 30, 2016
Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitmentJamie A Saxon, Taylor P Sherrill, Vasiliy V Polosukhin, et al.Journal of Medicinal Chemistry|April 18, 2022
Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based OptimizationKevin B Teuscher, Kenneth M Meyers, Qiangqiang Wei, et al.Journal of Medicinal Chemistry|June 2, 2018
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS SignalingJason R Abbott, Timothy R Hodges, R Nathan Daniels, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 23, 2016
PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 ResponsesJiqing Sai, Philip Owens, Sergey V Novitskiy, et al.Pageof 4