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Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase
Bradley J Newhouse, Steve Wenglowsky, Jonas Grina, et al.
ACS Medicinal Chemistry Letters
|
June 24, 2015
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series
Joachim Rudolph, Ignacio Aliagas, James J Crawford, et al.
Endocrinology
|
July 28, 2007
Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
William P Esler, Joachim Rudolph, Thomas H Claus, et al.
Nature Communications
|
December 16, 2021
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
Adrien Le Thomas, Elena Ferri, Scot Marsters, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 29, 2014
Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase
Steve Wenglowsky, Li Ren, Jonas Grina, et al.
Journal of Medicinal Chemistry
|
February 6, 2007
Indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail groups, a new class of potent PPAR alpha/gamma/delta pan agonists: synthesis, structure-activity relationship, and in vivo efficacy
Joachim Rudolph, Libing Chen, Dyuti Majumdar, et al.
Journal of Medicinal Chemistry
|
June 2, 2015
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors
James J Crawford, Wendy Lee, Ignacio Aliagas, et al.
Nature Communications
|
December 11, 2025
Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera
Jin Du, Elisia Villemure, Matthew Johnson, et al.
Cancer Cell
|
October 10, 2018
Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
Ivana Yen, Frances Shanahan, Mark Merchant, et al.
Journal of the National Cancer Institute
|
March 29, 2013
P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma
Christy C Ong, Adrian M Jubb, Diana Jakubiak, et al.
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Search research articles
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Showing results (21-30 of 52) with videos related to
Sort By:
Page
of 6
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Imidazo[4,5-b]pyridine inhibitors of B-Raf kinase
Bradley J Newhouse, Steve Wenglowsky, Jonas Grina, et al.
ACS Medicinal Chemistry Letters
|
June 24, 2015
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series
Joachim Rudolph, Ignacio Aliagas, James J Crawford, et al.
Endocrinology
|
July 28, 2007
Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
William P Esler, Joachim Rudolph, Thomas H Claus, et al.
Nature Communications
|
December 16, 2021
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
Adrien Le Thomas, Elena Ferri, Scot Marsters, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 29, 2014
Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase
Steve Wenglowsky, Li Ren, Jonas Grina, et al.
Journal of Medicinal Chemistry
|
February 6, 2007
Indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail groups, a new class of potent PPAR alpha/gamma/delta pan agonists: synthesis, structure-activity relationship, and in vivo efficacy
Joachim Rudolph, Libing Chen, Dyuti Majumdar, et al.
Journal of Medicinal Chemistry
|
June 2, 2015
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors
James J Crawford, Wendy Lee, Ignacio Aliagas, et al.
Nature Communications
|
December 11, 2025
Chemically-induced degradation of the endoplasmic-reticulum stress sensor IRE1 by a VHL-recruiting chimera
Jin Du, Elisia Villemure, Matthew Johnson, et al.
Cancer Cell
|
October 10, 2018
Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors
Ivana Yen, Frances Shanahan, Mark Merchant, et al.
Journal of the National Cancer Institute
|
March 29, 2013
P21-activated kinase 1 (PAK1) as a therapeutic target in BRAF wild-type melanoma
Christy C Ong, Adrian M Jubb, Diana Jakubiak, et al.
Page
of 6