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Joachim Rudolph

Showing results (31-40 of 52) with videos related to

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EMBO Reports|May 14, 2025
NRF2 supports non-small cell lung cancer growth independently of CBP/p300-enhanced glutathione synthesisRyan J Conrad, James A Mondo, Mike Lingjue Wang, et al.
ACS Medicinal Chemistry Letters|December 18, 2020
Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory ActivityRamsay E Beveridge, Heidi Ackerly Wallweber, Avi Ashkenazi, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2011
Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationshipsSteve Wenglowsky, Kateri A Ahrendt, Alex J Buckmelter, et al.
Cancer Research Communications|September 26, 2024
ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt PathwayJeffrey J Rodvold, Matthew Grimmer, Karen Ruiz, et al.
Nature Communications|December 15, 2020
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligandsElena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, et al.
Cancer Research|April 9, 2020
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor MicroenvironmentJonathan M Harnoss, Adrien Le Thomas, Mike Reichelt, et al.
Plos Biology|April 10, 2025
A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growthIratxe Zuazo-Gaztelu, David Lawrence, Ioanna Oikonomidi, et al.
ACS Medicinal Chemistry Letters|May 31, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase InhibitorMalcolm P Huestis, Matthew R Durk, Charles Eigenbrot, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 21, 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activityTill Maurer, Lindsay S Garrenton, Angela Oh, et al.
Nature Communications|November 3, 2025
Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22Elisia Villemure, Tom Januario, Mingshuo Zeng, et al.
Pageof 6

Showing results (31-40 of 52) with videos related to

Sort By:
Pageof 6
EMBO Reports|May 14, 2025
NRF2 supports non-small cell lung cancer growth independently of CBP/p300-enhanced glutathione synthesisRyan J Conrad, James A Mondo, Mike Lingjue Wang, et al.
ACS Medicinal Chemistry Letters|December 18, 2020
Identification of BRaf-Sparing Amino-Thienopyrimidines with Potent IRE1α Inhibitory ActivityRamsay E Beveridge, Heidi Ackerly Wallweber, Avi Ashkenazi, et al.
Bioorganic & Medicinal Chemistry Letters|August 2, 2011
Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationshipsSteve Wenglowsky, Kateri A Ahrendt, Alex J Buckmelter, et al.
Cancer Research Communications|September 26, 2024
ATF6 Promotes Colorectal Cancer Growth and Stemness by Regulating the Wnt PathwayJeffrey J Rodvold, Matthew Grimmer, Karen Ruiz, et al.
Nature Communications|December 15, 2020
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligandsElena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, et al.
Cancer Research|April 9, 2020
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor MicroenvironmentJonathan M Harnoss, Adrien Le Thomas, Mike Reichelt, et al.
Plos Biology|April 10, 2025
A nonenzymatic dependency on inositol-requiring enzyme 1 controls cancer cell cycle progression and tumor growthIratxe Zuazo-Gaztelu, David Lawrence, Ioanna Oikonomidi, et al.
ACS Medicinal Chemistry Letters|May 31, 2021
Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase InhibitorMalcolm P Huestis, Matthew R Durk, Charles Eigenbrot, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 21, 2012
Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activityTill Maurer, Lindsay S Garrenton, Angela Oh, et al.
Nature Communications|November 3, 2025
Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22Elisia Villemure, Tom Januario, Mingshuo Zeng, et al.
Pageof 6