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Kidney International|September 29, 2023
A novel multi-ancestry proteome-wide Mendelian randomization study implicates extracellular proteins, tubular cells, and fibroblasts in estimated glomerular filtration rate regulationMatthew B Lanktree, Nicolas Perrot, Andrew Smyth, et al.
The Journal of Biological Chemistry|March 28, 2019
Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathyRichard Van Krieken, Neel Mehta, Tony Wang, et al.
Molecular Metabolism|July 11, 2019
GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injuryKhrystyna Platko, Paul F Lebeau, Jae Hyun Byun, et al.
The Journal of Biological Chemistry|September 22, 2024
GDF10 is a negative regulator of vascular calcificationKhrystyna Platko, Gabriel Gyulay, Paul F Lebeau, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology|May 22, 2020
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle CellsKhrystyna Platko, Paul F Lebeau, Gabriel Gyulay, et al.
JCI Insight|December 21, 2018
Anti-GRP78 autoantibodies induce endothelial cell activation and accelerate the development of atherosclerotic lesionsElizabeth D Crane, Ali A Al-Hashimi, Jack Chen, et al.
Kidney360|September 30, 2022
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal LipotoxicityJae Hyun Byun, Paul F Lebeau, Khrystyna Platko, et al.
The Journal of Biological Chemistry|January 18, 2024
Restoration of the ER stress response protein TDAG51 in hepatocytes mitigates NAFLD in miceTamana R Yousof, Celeste C Bouchard, Mihnea Alb, et al.
JCI Insight|December 22, 2025
Inhibition of cell surface GRP78 and activated α2M interaction attenuates kidney fibrosisJackie Trink, Ifeanyi Kennedy Nmecha, Katrine Pilely, et al.
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