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Joanne R Mathiasen

Showing results (11-20 of 24) with videos related to

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Bioorganic & Medicinal Chemistry Letters|February 12, 2014
Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activityRobert L Hudkins, Kurt A Josef, Nadine C Becknell, et al.
Neuropharmacology|September 25, 2015
3-(1'-Cyclobutylspiro[4H-1,3-benzodioxine-2,4'-piperidine]-6-yl)-5,5-dimethyl-1,4-dihydropyridazin-6-one (CEP-32215), a new wake-promoting histamine H3 antagonist/inverse agonistRobert L Hudkins, John A Gruner, Rita Raddatz, et al.
European Journal of Medicinal Chemistry|April 2, 2015
3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activityRobert L Hudkins, Nadine C Becknell, Jacquelyn A Lyons, et al.
Bioorganic & Medicinal Chemistry Letters|September 28, 2011
Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activityReddeppa Reddy Dandu, John A Gruner, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters|December 7, 2011
4,5-dihydropyridazin-3-one derivatives as histamine H₃ receptor inverse agonistsRobert L Hudkins, Lisa D Aimone, Reddeppa Reddy Dandu, et al.
Bioorganic & Medicinal Chemistry Letters|February 1, 2012
4-phenoxypiperidine pyridazin-3-one histamine H(3) receptor inverse agonists demonstrating potent and robust wake promoting activityRobert L Hudkins, Allison L Zulli, Reddeppa reddy Dandu, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 2002
Mixed lineage kinase activity of indolocarbazole analoguesChikara Murakata, Masami Kaneko, George Gessner, et al.
Journal of Medicinal Chemistry|June 4, 2011
Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonistRobert L Hudkins, Rita Raddatz, Ming Tao, et al.
Brain Research|March 17, 2004
Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cellsJoanne R Mathiasen, Beth Ann W McKenna, Michael S Saporito, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 18, 2011
CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activitiesRita Raddatz, Robert L Hudkins, Joanne R Mathiasen, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Bioorganic & Medicinal Chemistry Letters|February 12, 2014
Discovery of (1R,6S)-5-[4-(1-cyclobutyl-piperidin-4-yloxy)-phenyl]-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one (R,S-4a): histamine H(3) receptor inverse agonist demonstrating potent cognitive enhancing and wake promoting activityRobert L Hudkins, Kurt A Josef, Nadine C Becknell, et al.
Neuropharmacology|September 25, 2015
3-(1'-Cyclobutylspiro[4H-1,3-benzodioxine-2,4'-piperidine]-6-yl)-5,5-dimethyl-1,4-dihydropyridazin-6-one (CEP-32215), a new wake-promoting histamine H3 antagonist/inverse agonistRobert L Hudkins, John A Gruner, Rita Raddatz, et al.
European Journal of Medicinal Chemistry|April 2, 2015
3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activityRobert L Hudkins, Nadine C Becknell, Jacquelyn A Lyons, et al.
Bioorganic & Medicinal Chemistry Letters|September 28, 2011
Synthesis and evaluation of pyridazinone-phenethylamine derivatives as selective and orally bioavailable histamine H3 receptor antagonists with robust wake-promoting activityReddeppa Reddy Dandu, John A Gruner, Joanne R Mathiasen, et al.
Bioorganic & Medicinal Chemistry Letters|December 7, 2011
4,5-dihydropyridazin-3-one derivatives as histamine H₃ receptor inverse agonistsRobert L Hudkins, Lisa D Aimone, Reddeppa Reddy Dandu, et al.
Bioorganic & Medicinal Chemistry Letters|February 1, 2012
4-phenoxypiperidine pyridazin-3-one histamine H(3) receptor inverse agonists demonstrating potent and robust wake promoting activityRobert L Hudkins, Allison L Zulli, Reddeppa reddy Dandu, et al.
Bioorganic & Medicinal Chemistry Letters|January 5, 2002
Mixed lineage kinase activity of indolocarbazole analoguesChikara Murakata, Masami Kaneko, George Gessner, et al.
Journal of Medicinal Chemistry|June 4, 2011
Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonistRobert L Hudkins, Rita Raddatz, Ming Tao, et al.
Brain Research|March 17, 2004
Inhibition of mixed lineage kinase 3 attenuates MPP+-induced neurotoxicity in SH-SY5Y cellsJoanne R Mathiasen, Beth Ann W McKenna, Michael S Saporito, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 18, 2011
CEP-26401 (irdabisant), a potent and selective histamine H₃ receptor antagonist/inverse agonist with cognition-enhancing and wake-promoting activitiesRita Raddatz, Robert L Hudkins, Joanne R Mathiasen, et al.
Pageof 3