Showing results (1-10 of 14) with videos related to
Sort By:
Pageof 2
Angewandte Chemie (International Ed. in English)|September 23, 2003
Solution-phase combinatorial libraries: modulating cellular signaling by targeting protein-protein or protein-DNA interactionsDale L Boger, Joel Desharnais, Kevin CappsJournal of the American Chemical Society|January 24, 2002
Erythropoietin mimetics derived from solution phase combinatorial librariesJoel Goldberg, Qing Jin, Yves Ambroise, et al.Biochemistry|November 27, 2002
Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GARYan Zhang, Joel Desharnais, Samantha E Greasley, et al.Bioorganic & Medicinal Chemistry Letters|May 3, 2005
A facile route to paclitaxel C-10 carbamatesCarlo Ballatore, Simon E Aspland, Rosario Castillo, et al.Bioorganic & Medicinal Chemistry|September 18, 2003
Design, synthesis and biological evaluation of 10-CF3CO-DDACTHF analogues and derivatives as inhibitors of GAR Tfase and the de novo purine biosynthetic pathwayJoel Desharnais, Inkyu Hwang, Yan Zhang, et al.Proceedings of the National Academy of Sciences of the United States of America|March 14, 2002
Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblastsThorsten Berg, Steven B Cohen, Joel Desharnais, et al.Bioorganic & Medicinal Chemistry|September 18, 2003
Design, synthesis, and biological evaluation of simplified alpha-keto heterocycle, trifluoromethyl ketone, and formyl substituted folate analogues as potential inhibitors of GAR transformylase and AICAR transformylaseThomas H Marsilje, Michael P Hedrick, Joel Desharnais, et al.Bioorganic & Medicinal Chemistry|September 18, 2003
10-(2-benzoxazolcarbonyl)-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid: a potential inhibitor of GAR transformylase and AICAR transformylaseThomas H Marsilje, Michael P Hedrick, Joel Desharnais, et al.Bioorganic & Medicinal Chemistry Letters|July 28, 2006
Kinase-mediated trapping of bi-functional conjugates of paclitaxel or vinblastine with thymidine in cancer cellsSimon E Aspland, Carlo Ballatore, Rosario Castillo, et al.Biochemistry|May 21, 2003
Rational design, synthesis, evaluation, and crystal structure of a potent inhibitor of human GAR Tfase: 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acidYan Zhang, Joel Desharnais, Thomas H Marsilje, et al.Pageof 2