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Regulatory Toxicology and Pharmacology : RTP
|
June 27, 2012
Application of the threshold of toxicological concern concept when applied to pharmaceutical manufacturing operations intended for short-term clinical trials
Joel P Bercu, David G Dolan
Regulatory Toxicology and Pharmacology : RTP
|
August 28, 2012
Advancing toxicology in RiskMAPP: setting ADEs based on the subsequent drug substance
Joel P Bercu, Rizwan Sharnez, David G Dolan
International Journal of Toxicology
|
December 8, 2009
Overview of genotoxic impurities in pharmaceutical development
Joel P Bercu, Krista L Dobo, Elmar Gocke, et al.
Regulatory Toxicology and Pharmacology : RTP
|
June 14, 2008
Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance
Joel P Bercu, Wherly P Hoffman, Cindy Lee, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 31, 2015
Threshold of toxicological concern (TTC) for developmental and reproductive toxicity of anticancer compounds
Brad Stanard, David G Dolan, William Hanneman, et al.
Regulatory Toxicology and Pharmacology : RTP
|
March 12, 2008
Human health risk assessments for three neuropharmaceutical compounds in surface waters
Joel P Bercu, Neil J Parke, Janice M Fiori, et al.
Chemical Research in Toxicology
|
January 28, 2009
A strategy for the risk assessment of human genotoxic metabolites
Krista L Dobo, R Scott Obach, Debra Luffer-Atlas, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 29, 2016
Point of departure (PoD) selection for the derivation of acceptable daily exposures (ADEs) for active pharmaceutical ingredients (APIs)
Joel P Bercu, Eric J Morinello, Claudia Sehner, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
|
September 28, 2023
Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiethylamine
Joel P Bercu, Shaofei Zhang, Zhanna Sobol, et al.
International Journal of Toxicology
|
February 2, 2021
Deriving Compound-Specific Exposure Limits for Chemicals Used in Pharmaceutical Synthesis: Challenges in Expert Decision-Making Exemplified Through a Case Study-Based Workshop
William C Drewe, Krista L Dobo, Zhanna Sobol, et al.
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of 3
Search research articles
Search
Showing results (1-10 of 27) with videos related to
Sort By:
Page
of 3
Regulatory Toxicology and Pharmacology : RTP
|
June 27, 2012
Application of the threshold of toxicological concern concept when applied to pharmaceutical manufacturing operations intended for short-term clinical trials
Joel P Bercu, David G Dolan
Regulatory Toxicology and Pharmacology : RTP
|
August 28, 2012
Advancing toxicology in RiskMAPP: setting ADEs based on the subsequent drug substance
Joel P Bercu, Rizwan Sharnez, David G Dolan
International Journal of Toxicology
|
December 8, 2009
Overview of genotoxic impurities in pharmaceutical development
Joel P Bercu, Krista L Dobo, Elmar Gocke, et al.
Regulatory Toxicology and Pharmacology : RTP
|
June 14, 2008
Quantitative assessment of cumulative carcinogenic risk for multiple genotoxic impurities in a new drug substance
Joel P Bercu, Wherly P Hoffman, Cindy Lee, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 31, 2015
Threshold of toxicological concern (TTC) for developmental and reproductive toxicity of anticancer compounds
Brad Stanard, David G Dolan, William Hanneman, et al.
Regulatory Toxicology and Pharmacology : RTP
|
March 12, 2008
Human health risk assessments for three neuropharmaceutical compounds in surface waters
Joel P Bercu, Neil J Parke, Janice M Fiori, et al.
Chemical Research in Toxicology
|
January 28, 2009
A strategy for the risk assessment of human genotoxic metabolites
Krista L Dobo, R Scott Obach, Debra Luffer-Atlas, et al.
Regulatory Toxicology and Pharmacology : RTP
|
May 29, 2016
Point of departure (PoD) selection for the derivation of acceptable daily exposures (ADEs) for active pharmaceutical ingredients (APIs)
Joel P Bercu, Eric J Morinello, Claudia Sehner, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
|
September 28, 2023
Comparison of the transgenic rodent mutation assay, error corrected next generation duplex sequencing, and the alkaline comet assay to detect dose-related mutations following exposure to N-nitrosodiethylamine
Joel P Bercu, Shaofei Zhang, Zhanna Sobol, et al.
International Journal of Toxicology
|
February 2, 2021
Deriving Compound-Specific Exposure Limits for Chemicals Used in Pharmaceutical Synthesis: Challenges in Expert Decision-Making Exemplified Through a Case Study-Based Workshop
William C Drewe, Krista L Dobo, Zhanna Sobol, et al.
Page
of 3