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Bioorganic & Medicinal Chemistry Letters
|
September 1, 2007
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
Christopher L Hamblett, Joey L Methot, Dawn M Mampreian, et al.
Journal of Medicinal Chemistry
|
April 16, 2019
Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability
Joey L Methot, Hua Zhou, Sam D Kattar, et al.
Nature Communications
|
January 3, 2026
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors
Rachel L Palte, Mihir Mandal, Justyna Sikorska, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 10, 2008
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
Joey L Methot, Prasun K Chakravarty, Melissa Chenard, et al.
Journal of Medicinal Chemistry
|
April 2, 2021
Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators
Joey L Methot, Hua Zhou, Meredeth A McGowan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2015
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
Christian Fischer, Susan L Zultanski, Hua Zhou, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 6, 2015
Potent benzoazepinone γ-secretase modulators with improved bioavailability
Joey L Methot, Christian Fischer, Chaomin Li, et al.
RSC Medicinal Chemistry
|
August 6, 2021
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors
Anmol Gulati, Charles S Yeung, Blair Lapointe, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
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of 3
Search research articles
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Showing results (21-30 of 29) with videos related to
Sort By:
Page
of 3
You have reached the last page of results.
This site can display upto 29 results.
Bioorganic & Medicinal Chemistry Letters
|
September 1, 2007
The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
Christopher L Hamblett, Joey L Methot, Dawn M Mampreian, et al.
Journal of Medicinal Chemistry
|
April 16, 2019
Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability
Joey L Methot, Hua Zhou, Sam D Kattar, et al.
Nature Communications
|
January 3, 2026
WRN structural flexibility showcased through fragment-based lead discovery of inhibitors
Rachel L Palte, Mihir Mandal, Justyna Sikorska, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 10, 2008
Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2)
Joey L Methot, Prasun K Chakravarty, Melissa Chenard, et al.
Journal of Medicinal Chemistry
|
April 2, 2021
Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators
Joey L Methot, Hua Zhou, Meredeth A McGowan, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 28, 2015
Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys
Christian Fischer, Susan L Zultanski, Hua Zhou, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 6, 2015
Potent benzoazepinone γ-secretase modulators with improved bioavailability
Joey L Methot, Christian Fischer, Chaomin Li, et al.
RSC Medicinal Chemistry
|
August 6, 2021
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors
Anmol Gulati, Charles S Yeung, Blair Lapointe, et al.
Journal of Medicinal Chemistry
|
December 8, 2022
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1<i>H</i>-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease
David A Candito, Vladimir Simov, Anmol Gulati, et al.
Page
of 3