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ACS Chemical Biology|February 24, 2023
Biochemical and Structural Characterization of a Peptidic Inhibitor of the YAP:TEAD Interaction That Binds to the α-Helix Pocket on TEADYannick Mesrouze, Hanspeter Gubler, Frédéric Villard, et al.The Journal of Biological Chemistry|June 9, 2007
Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanismJoerg Kallen, Rene Lattmann, Rene Beerli, et al.Journal of Biomolecular Screening|January 1, 2015
Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologiesPeter S Kutchukian, Anne Mai Wassermann, Mika K Lindvall, et al.Analytical Biochemistry|June 21, 2005
Synthesis and characterization of fluorescent ubiquitin derivatives as highly sensitive substrates for the deubiquitinating enzymes UCH-L3 and USP-2Aline Tirat, Alain Schilb, Virginie Riou, et al.Angewandte Chemie (International Ed. in English)|November 23, 2016
Bioorthogonal Probes for the Study of MDM2-p53 Inhibitors in Cells and Development of High-Content Screening Assays for Drug DiscoveryPier Luca D'Alessandro, Nicole Buschmann, Markus Kaufmann, et al.RSC Chemical Biology|January 3, 2022
Discovery, X-ray structure and CPP-conjugation enabled uptake of p53/MDM2 macrocyclic peptide inhibitorsAnselm F L Schneider, Joerg Kallen, Johannes Ottl, et al.Nature Chemical Biology|July 17, 2007
Identification and mechanistic characterization of low-molecular-weight inhibitors for HuRNicole-Claudia Meisner, Martin Hintersteiner, Kurt Mueller, et al.Journal of Medicinal Chemistry|July 11, 2018
Optimizing a Weakly Binding Fragment into a Potent RORγt Inverse Agonist with Efficacy in an in Vivo Inflammation ModelDavid A Carcache, Anna Vulpetti, Joerg Kallen, et al.Nature Communications|July 4, 2026
Specificity and exon target space of splicing modifying compoundsFelina Lenkeit, Judith Knehr, Marc Altorfer, et al.Journal of Medicinal Chemistry|November 16, 2019
Structure-Based and Property-Driven Optimization of <i>N</i>-Aryl Imidazoles toward Potent and Selective Oral RORγt InhibitorsKlemens Hoegenauer, Joerg Kallen, Eloísa Jiménez-Núñez, et al.Pageof 3