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Archives of Toxicology|June 28, 2018
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell linesFiona R Kolbinger, Emily Koeneke, Johannes Ridinger, et al.
Journal of Medicinal Chemistry|April 10, 2019
Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is ImplicatedMagalie Géraldy, Michael Morgen, Peter Sehr, et al.
Scientific Reports|July 4, 2018
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistanceJohannes Ridinger, Emily Koeneke, Fiona R Kolbinger, et al.
Cell Death & Disease|August 25, 2017
Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistanceCorinna Bingel, Emily Koeneke, Johannes Ridinger, et al.
International Journal of Molecular Sciences|July 27, 2022
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma ActivitySalma Darwish, Ehab Ghazy, Tino Heimburg, et al.
Chemmedchem|April 30, 2020
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 InhibitorsMichael Morgen, Raphael R Steimbach, Magalie Géraldy, et al.
European Journal of Medicinal Chemistry|March 20, 2022
Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cellsPatrik Zeyen, Yanira Zeyn, Daniel Herp, et al.
Cancers|September 10, 2021
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for NeuroblastomaMichael Müller, Lisa Rösch, Sara Najafi, et al.
Chembiochem : a European Journal of Chemical Biology|May 24, 2022
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target EngagementDaniel Herp, Johannes Ridinger, Dina Robaa, et al.
Journal of the American Chemical Society|October 6, 2022
Aza-SAHA Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 KnockoutRaphael R Steimbach, Corey J Herbst-Gervasoni, Severin Lechner, et al.
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