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The Journal of Biological Chemistry|September 4, 2003
The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition poreAndrea M Cesura, Emmanuel Pinard, Robert Schubenel, et al.Neuropharmacology|April 15, 2004
Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodentGuy A Higgins, Theresa M Ballard, James N C Kew, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|March 29, 2002
Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brainRamanjit Gill, Marc Soriano, Klas Blomgren, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|August 2, 2002
Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivityTheresa M Ballard, Meike Pauly-Evers, Guy A Higgins, et al.Brain Research. Molecular Brain Research|January 18, 2003
Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellumPari Malherbe, James N C Kew, J Grayson Richards, et al.Chemmedchem|December 7, 2007
Asymmetric synthesis and receptor pharmacology of the group II mGlu receptor ligand (1S,2R,3R,5R,6S)-2-amino-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid-HYDIAThomas J Woltering, Geo Adam, Philipp Huguenin, et al.Plos One|November 26, 2009
Early-onset and robust amyloid pathology in a new homozygous mouse model of Alzheimer's diseaseAntje Willuweit, Joachim Velden, Robert Godemann, et al.The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|October 3, 2003
PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammationJ Grayson Richards, Guy A Higgins, Abdel-Mouttalib Ouagazzal, et al.Frontiers in Pharmacology|February 3, 2023
SDI-118, a novel procognitive SV2A modulator: First-in-human randomized controlled trial including PET/fMRI assessment of target engagementWouter Botermans, Michel Koole, Koen Van Laere, et al.Neurobiology of Disease|September 16, 2014
Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic miceEve Peeraer, Astrid Bottelbergs, Kristof Van Kolen, et al.Pageof 3