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John A. Flygare

Showing results (11-20 of 34) with videos related to

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Biochemistry|July 9, 2003
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)Matthew C Franklin, Saloumeh Kadkhodayan, Heidi Ackerly, et al.
Journal of Pharmaceutical Sciences|January 15, 2019
Cyclodextrin Reduces Intravenous Toxicity of a Model CompoundPriscilla Mantik, Minli Xie, Harvey Wong, et al.
Chemical Science|April 29, 2017
Decoupling stability and release in disulfide bonds with antibody-small molecule conjugatesThomas H Pillow, Jack D Sadowsky, Donglu Zhang, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|September 8, 2012
Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacologyRebecca I Erickson, Jacqueline Tarrant, Gary Cain, et al.
Journal of Medicinal Chemistry|September 5, 2024
Discovery and Evaluation of TLR-Targeted Immune AgonistsNatalia Chernyak, Bhagyashree Bhagwat, Saraswathi Naravula, et al.
ACS Chemical Biology|June 5, 2009
Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonistsChudi Ndubaku, Eugene Varfolomeev, Lan Wang, et al.
Cell|November 21, 2007
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosisEugene Varfolomeev, John W Blankenship, Sarah M Wayson, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 18, 2013
Learning and confirming with preclinical studies: modeling and simulation in the discovery of GDC-0917, an inhibitor of apoptosis proteins antagonistHarvey Wong, Stephen E Gould, Nageshwar Budha, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|July 31, 2012
Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysisHarvey Wong, Nageshwar R Budha, Kristina West, et al.
Journal of Medicinal Chemistry|March 4, 2011
Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activityBrad E Sleebs, Peter E Czabotar, Wayne J Fairbrother, et al.
Pageof 4

Showing results (11-20 of 34) with videos related to

Sort By:
Pageof 4
Biochemistry|July 9, 2003
Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)Matthew C Franklin, Saloumeh Kadkhodayan, Heidi Ackerly, et al.
Journal of Pharmaceutical Sciences|January 15, 2019
Cyclodextrin Reduces Intravenous Toxicity of a Model CompoundPriscilla Mantik, Minli Xie, Harvey Wong, et al.
Chemical Science|April 29, 2017
Decoupling stability and release in disulfide bonds with antibody-small molecule conjugatesThomas H Pillow, Jack D Sadowsky, Donglu Zhang, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|September 8, 2012
Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacologyRebecca I Erickson, Jacqueline Tarrant, Gary Cain, et al.
Journal of Medicinal Chemistry|September 5, 2024
Discovery and Evaluation of TLR-Targeted Immune AgonistsNatalia Chernyak, Bhagyashree Bhagwat, Saraswathi Naravula, et al.
ACS Chemical Biology|June 5, 2009
Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonistsChudi Ndubaku, Eugene Varfolomeev, Lan Wang, et al.
Cell|November 21, 2007
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosisEugene Varfolomeev, John W Blankenship, Sarah M Wayson, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 18, 2013
Learning and confirming with preclinical studies: modeling and simulation in the discovery of GDC-0917, an inhibitor of apoptosis proteins antagonistHarvey Wong, Stephen E Gould, Nageshwar Budha, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|July 31, 2012
Dogs are more sensitive to antagonists of inhibitor of apoptosis proteins than rats and humans: a translational toxicokinetic/toxicodynamic analysisHarvey Wong, Nageshwar R Budha, Kristina West, et al.
Journal of Medicinal Chemistry|March 4, 2011
Quinazoline sulfonamides as dual binders of the proteins B-cell lymphoma 2 and B-cell lymphoma extra long with potent proapoptotic cell-based activityBrad E Sleebs, Peter E Czabotar, Wayne J Fairbrother, et al.
Pageof 4