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John C Murray

Showing results (11-20 of 19) with videos related to

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Journal of the American Academy of Dermatology|July 8, 2008
A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiationJohn C Murray, James A Burch, Robert D Streilein, et al.
The Journal of Organic Chemistry|November 3, 2017
Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH ArylationLuis A Martinez-Alsina, John C Murray, Leanne M Buzon, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 17, 2003
In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximesAmit S Kalgutkar, Hang T Nguyen, Alfin D N Vaz, et al.
The Journal of Organic Chemistry|February 27, 2013
Stereoselective synthesis of spiropiperidines as BACE-1 aspartyl protease inhibitors via late stage N-arylation of a 1,8-diazaspiro[4.5]dec-3-en-2-one pharmacophoreChe-Wah Lee, Ricardo Lira, Jason Dutra, et al.
Journal of Medicinal Chemistry|February 24, 2015
2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonistsYves A Chantigny, John C Murray, Edward F Kleinman, et al.
Journal of Medicinal Chemistry|February 26, 2009
Octahydrophenanthrene-2,7-diol analogues as dissociated glucocorticoid receptor agonists: discovery and lead explorationRalph P Robinson, Leonard Buckbinder, Amber I Haugeto, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry|April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Pageof 2

Showing results (11-20 of 19) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 19 results.
Journal of the American Academy of Dermatology|July 8, 2008
A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiationJohn C Murray, James A Burch, Robert D Streilein, et al.
The Journal of Organic Chemistry|November 3, 2017
Spiropiperidine Sultam and Lactam Templates: Diastereoselective Overman Rearrangement and Metathesis followed by NH ArylationLuis A Martinez-Alsina, John C Murray, Leanne M Buzon, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 17, 2003
In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximesAmit S Kalgutkar, Hang T Nguyen, Alfin D N Vaz, et al.
The Journal of Organic Chemistry|February 27, 2013
Stereoselective synthesis of spiropiperidines as BACE-1 aspartyl protease inhibitors via late stage N-arylation of a 1,8-diazaspiro[4.5]dec-3-en-2-one pharmacophoreChe-Wah Lee, Ricardo Lira, Jason Dutra, et al.
Journal of Medicinal Chemistry|February 24, 2015
2-Aryl-3-methyloctahydrophenanthrene-2,3,7-triols as potent dissociated glucocorticoid receptor agonistsYves A Chantigny, John C Murray, Edward F Kleinman, et al.
Journal of Medicinal Chemistry|February 26, 2009
Octahydrophenanthrene-2,7-diol analogues as dissociated glucocorticoid receptor agonists: discovery and lead explorationRalph P Robinson, Leonard Buckbinder, Amber I Haugeto, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Medicinal Chemistry|April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Pageof 2