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The Journal of Clinical Investigation|November 19, 2019
Apelin directs endothelial cell differentiation and vascular repair following immune-mediated injuryAndrew G Masoud, Jiaxin Lin, Abul K Azad, et al.Cell Reports|December 14, 2024
SARS-CoV-2 3CL<sup>pro</sup> (main protease) regulates caspase activation of gasdermin-D/E pores leading to secretion and extracellular activity of 3CL<sup>pro</sup>Peter M Grin, Kaushal Baid, Hugo C R de Jesus, et al.ACS Central Science|May 1, 2023
SARS-CoV-2 M<sup>pro</sup> Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward AntiviralsSizhu Amelia Chen, Elena Arutyunova, Jimmy Lu, et al.European Journal of Medicinal Chemistry|June 12, 2021
Improved SARS-CoV-2 M<sup>pro</sup> inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studiesWayne Vuong, Conrad Fischer, Muhammad Bashir Khan, et al.RSC Medicinal Chemistry|November 15, 2021
Peptidomimetic nitrile warheads as SARS-CoV-2 3CL protease inhibitorsBing Bai, Elena Arutyunova, Muhammad Bashir Khan, et al.JCI Insight|June 18, 2026
Apelin analog treatment reverses severe pulmonary arterial hypertension and right ventricular heart failureJennie Vu, Pavel Zhabyeyev, Kemar J Brown, et al.Nature Communications|September 13, 2023
Genetically encoded discovery of perfluoroaryl macrocycles that bind to albumin and exhibit extended circulation in vivoJeffrey Y K Wong, Arunika I Ekanayake, Serhii Kharchenko, et al.Clinical Immunology (Orlando, Fla.)|March 12, 2021
Tityus serrulatus scorpion venom as a potential drug source for Chagas' disease: Trypanocidal and immunomodulatory activityPollyana Maria de Oliveira Pimentel, Diego Rodney Rodrigues de Assis, Melisa Gualdrón-Lopez, et al.Cell Reports|October 21, 2021
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CL<sup>pro</sup> substrate degradomeIsabel Pablos, Yoan Machado, Hugo C Ramos de Jesus, et al.Journal of Medicinal Chemistry|July 9, 2021
Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and <i>in Vitro</i> Biological StabilityBing Bai, Alexandr Belovodskiy, Mostofa Hena, et al.Pageof 21