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Expert Opinion on Therapeutic Patents|October 21, 2020
The therapeutic potential of PROTACsAndrew B Benowitz, Katherine L Jones, John D Harling
Organic & Biomolecular Chemistry|October 22, 2008
Phosphinates as new electrophilic partners for cross-coupling reactionsJun Guo, John D Harling, Patrick G Steel, et al.
Organic & Biomolecular Chemistry|October 19, 2007
One-pot synthesis of benzothiazolines and napthathiazolines via cascade ortho-lithiation, cyclisation and elimination of N-arylsulfonyl lactamsJohn D Harling, Patrick G Steel, Tom M Woods, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|May 3, 2005
Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20s proteasome inhibitor, clasto-lactacystin beta-lactoneTimothy J Donohoe, Herman O Sintim, Leena Sisangia, et al.
Chemical Communications (Cambridge, England)|April 17, 2020
A caged E3 ligase ligand for PROTAC-mediated protein degradation with lightCyrille S Kounde, Maria M Shchepinova, Charlie N Saunders, et al.
Chemical Science|June 24, 2021
Activating mechanosensitive channels embedded in droplet interface bilayers using membrane asymmetryRobert Strutt, James W Hindley, Jordan Gregg, et al.
RSC Medicinal Chemistry|December 25, 2024
Expanding the reaction toolbox for nanoscale direct-to-biology PROTAC synthesis and biological evaluationRebecca Stevens, Harry J Shrives, Jenni Cryan, et al.
ACS Medicinal Chemistry Letters|July 18, 2019
Targeting IRAK4 for Degradation with PROTACsJoao Nunes, Grant A McGonagle, Jessica Eden, et al.
ACS Chemical Biology|June 13, 2015
HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion ProteinsDennis L Buckley, Kanak Raina, Nicole Darricarrere, et al.
Molecular Pharmacology|June 18, 2002
SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7Gareth J Inman, Francisco J Nicolás, James F Callahan, et al.
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