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Journal of Medicinal Chemistry|April 24, 2020
Facts, Patterns, and Principles in Drug Discovery: Appraising the Rule of 5 with Measured Physicochemical DataChristopher P Tinworth, Robert J YoungACS Chemical Biology|February 27, 2019
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent BindingChristopher P Tinworth, Hannah Lithgow, Lars Dittus, et al.ACS Chemical Biology|July 23, 2020
Structural Insights into PROTAC-Mediated Degradation of Bcl-xLChun-Wa Chung, Han Dai, Esther Fernandez, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|September 23, 2020
Computational Mapping of Dirhodium(II) CatalystsAdam I Green, Christopher P Tinworth, Stuart Warriner, et al.Expert Opinion on Therapeutic Patents|October 21, 2020
The therapeutic potential of PROTACsAndrew B Benowitz, Katherine L Jones, John D HarlingChemical Communications (Cambridge, England)|September 6, 2022
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)Qisi Zhang, Cyrille S Kounde, Milon Mondal, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|May 28, 2020
Activity-Directed Synthesis of Inhibitors of the p53/hDM2 Protein-Protein InteractionAdam I Green, Fruzsina Hobor, Christopher P Tinworth, et al.Organic & Biomolecular Chemistry|October 22, 2008
Phosphinates as new electrophilic partners for cross-coupling reactionsJun Guo, John D Harling, Patrick G Steel, et al.Organic & Biomolecular Chemistry|October 19, 2007
One-pot synthesis of benzothiazolines and napthathiazolines via cascade ortho-lithiation, cyclisation and elimination of N-arylsulfonyl lactamsJohn D Harling, Patrick G Steel, Tom M Woods, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|May 3, 2005
Utility of the ammonia-free Birch reduction of electron-deficient pyrroles: total synthesis of the 20s proteasome inhibitor, clasto-lactacystin beta-lactoneTimothy J Donohoe, Herman O Sintim, Leena Sisangia, et al.Pageof 4