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Journal of Medicinal Chemistry|August 25, 2021
Optimization of a Series of RIPK2 PROTACsAfjal H Miah, Ian E D Smith, Mark Rackham, et al.Angewandte Chemie (International Ed. in English)|August 20, 2021
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACsRobert P Law, Joao Nunes, Chun-Wa Chung, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping StrategyCatherine M Alder, Martin Ambler, Amanda J Campbell, et al.Communications Biology|March 22, 2020
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2Alina Mares, Afjal H Miah, Ian E D Smith, et al.Bioorganic & Medicinal Chemistry Letters|February 26, 2011
The discovery of potent and long-acting oral factor Xa inhibitors with tetrahydroisoquinoline and benzazepine P4 motifsNigel S Watson, Carl Adams, David Belton, et al.Bioorganic & Medicinal Chemistry Letters|February 26, 2011
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifsRobert J Young, Carl Adams, Mike Blows, et al.Nature Chemical Biology|June 16, 2015
Catalytic in vivo protein knockdown by small-molecule PROTACsDaniel P Bondeson, Alina Mares, Ian E D Smith, et al.Bioorganic & Medicinal Chemistry Letters|December 17, 2009
Structure and property based design of factor Xa inhibitors: pyrrolidin-2-ones with monoaryl P4 motifsSavvas Kleanthous, Alan D Borthwick, David Brown, et al.Pageof 3