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Nature Cancer
|
December 27, 2023
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers
Marc Payton, Brian Belmontes, Kelly Hanestad, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer's disease
Jian Jeffrey Chen, Wenyuan Qian, Kaustav Biswas, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Nature
|
November 1, 2019
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Jude Canon, Karen Rex, Anne Y Saiki, et al.
Journal of Medicinal Chemistry
|
December 4, 2014
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease
Timothy D Cushing, Xiaolin Hao, Youngsook Shin, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
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of 3
Search research articles
Search
Showing results (21-30 of 27) with videos related to
Sort By:
Page
of 3
You have reached the last page of results.
This site can display upto 27 results.
Nature Cancer
|
December 27, 2023
Small-molecule inhibition of kinesin KIF18A reveals a mitotic vulnerability enriched in chromosomally unstable cancers
Marc Payton, Brian Belmontes, Kelly Hanestad, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
Discovery of 2-methylpyridine-based biaryl amides as γ-secretase modulators for the treatment of Alzheimer's disease
Jian Jeffrey Chen, Wenyuan Qian, Kaustav Biswas, et al.
Journal of Medicinal Chemistry
|
May 3, 2012
Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases
Adrian L Smith, Noel D D'Angelo, Yunxin Y Bo, et al.
Nature
|
November 1, 2019
The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity
Jude Canon, Karen Rex, Anne Y Saiki, et al.
Journal of Medicinal Chemistry
|
December 4, 2014
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease
Timothy D Cushing, Xiaolin Hao, Youngsook Shin, et al.
Journal of Medicinal Chemistry
|
August 18, 2012
Selective class I phosphoinositide 3-kinase inhibitors: optimization of a series of pyridyltriazines leading to the identification of a clinical candidate, AMG 511
Mark H Norman, Kristin L Andrews, Yunxin Y Bo, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
Page
of 3