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Behavioural Brain Research|May 29, 2020
Rapastinel, an NMDAR positive modulator, produces distinct behavioral, sleep, and EEG profiles compared with ketaminePradeep Banerjee, John E Donello, Brendan Hare, et al.
Molecular and Cellular Biology|March 9, 2002
CRM1-dependent function of a cis-acting RNA export elementIleana Popa, Matthew E Harris, John E Donello, et al.
Pharmaceuticals (Basel, Switzerland)|February 26, 2025
Demystifying the Antidepressant Mechanism of Action of Stinels, a Novel Class of Neuroplastogens: Positive Allosteric Modulators of the NMDA ReceptorJohn E Donello, Roger S McIntyre, Donald B Pickel, et al.
The International Journal of Neuropsychopharmacology|July 26, 2022
Zelquistinel Is an Orally Bioavailable Novel NMDA Receptor Allosteric Modulator That Exhibits Rapid and Sustained Antidepressant-Like EffectsJeffrey S Burgdorf, Xiao-Lei Zhang, Patric K Stanton, et al.
Neuropharmacology|February 24, 2024
The NMDA receptor modulator zelquistinel durably relieves behavioral deficits in three mouse models of autism spectrum disorderMathieu Fonteneau, Agathe Brugoux, Déborah Jaccaz, et al.
Neuroreport|May 20, 2022
Extracellular application of the N-methyl-D-aspartate receptor allosteric modulator rapastinel acts remotely to regulate Ca2+ inactivation at an intracellular locusXiao-Lei Zhang, Nils A Berglund, Jeffrey S Burgdorf, et al.
Anesthesiology|February 6, 2009
Alpha-1-adrenergic receptor agonist activity of clinical alpha-adrenergic receptor agonists interferes with alpha-2-mediated analgesiaDaniel W Gil, Cynthia V Cheevers, Karen M Kedzie, et al.
Anesthesiology|May 5, 2011
A peripheral adrenoceptor-mediated sympathetic mechanism can transform stress-induced analgesia into hyperalgesiaJohn E Donello, Yun Guan, Mingting Tian, et al.
Neuropharmacology|August 8, 2024
Zelquistinel acts at an extracellular binding domain to modulate intracellular calcium inactivation of N-methyl-d-aspartate receptorsXiao-Lei Zhang, Yong-Xin Li, Nils Berglund, et al.
The International Journal of Neuropsychopharmacology|December 14, 2018
Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like EffectsJohn E Donello, Pradeep Banerjee, Yong-Xin Li, et al.
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