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John Eksterowicz

Showing results (11-20 of 24) with videos related to

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Molecular Cancer Therapeutics|January 9, 2015
The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic AgentsJude Canon, Tao Osgood, Steven H Olson, et al.
Bioorganic & Medicinal Chemistry Letters|July 28, 2006
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivoJeffrey R Spencer, Martin Sendzik, Jason Oeh, et al.
Journal of Medicinal Chemistry|August 10, 2018
Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101)Yosup Rew, Xiaohui Du, John Eksterowicz, et al.
Bioorganic & Medicinal Chemistry Letters|February 5, 2013
Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structuresKexue Li, Lawrence R McGee, Ben Fisher, et al.
Journal of Medicinal Chemistry|September 1, 2020
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine ProductionXiaohui Du, Jared Moore, Brian R Blank, et al.
Molecular Cancer Therapeutics|February 15, 2014
Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemiaKathleen Keegan, Cong Li, Zhihong Li, et al.
ACS Medicinal Chemistry Letters|August 23, 2014
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 InteractionMing Yu, Yingcai Wang, Jiang Zhu, et al.
Bioorganic & Medicinal Chemistry Letters|June 21, 2006
Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducersVincent W-F Tai, David Sperandio, Emma J Shelton, et al.
Journal of Medicinal Chemistry|October 26, 2025
Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor ImmunosuppressionJared T Moore, Hiroyuki Kawai, Brian R Blank, et al.
Journal of Medicinal Chemistry|March 8, 2014
Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteresAna Z Gonzalez, Zhihong Li, Hilary P Beck, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Molecular Cancer Therapeutics|January 9, 2015
The MDM2 Inhibitor AMG 232 Demonstrates Robust Antitumor Efficacy and Potentiates the Activity of p53-Inducing Cytotoxic AgentsJude Canon, Tao Osgood, Steven H Olson, et al.
Bioorganic & Medicinal Chemistry Letters|July 28, 2006
Evaluation of antitumor properties of novel saframycin analogs in vitro and in vivoJeffrey R Spencer, Martin Sendzik, Jason Oeh, et al.
Journal of Medicinal Chemistry|August 10, 2018
Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101)Yosup Rew, Xiaohui Du, John Eksterowicz, et al.
Bioorganic & Medicinal Chemistry Letters|February 5, 2013
Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structuresKexue Li, Lawrence R McGee, Ben Fisher, et al.
Journal of Medicinal Chemistry|September 1, 2020
Orally Bioavailable Small-Molecule CD73 Inhibitor (OP-5244) Reverses Immunosuppression through Blockade of Adenosine ProductionXiaohui Du, Jared Moore, Brian R Blank, et al.
Molecular Cancer Therapeutics|February 15, 2014
Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemiaKathleen Keegan, Cong Li, Zhihong Li, et al.
ACS Medicinal Chemistry Letters|August 23, 2014
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 InteractionMing Yu, Yingcai Wang, Jiang Zhu, et al.
Bioorganic & Medicinal Chemistry Letters|June 21, 2006
Discovery and structure-activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducersVincent W-F Tai, David Sperandio, Emma J Shelton, et al.
Journal of Medicinal Chemistry|October 26, 2025
Discovery of ORIC-533, an Orally Bioavailable CD73 Inhibitor That Maintains Activity in High AMP Environments to Reverse Tumor ImmunosuppressionJared T Moore, Hiroyuki Kawai, Brian R Blank, et al.
Journal of Medicinal Chemistry|March 8, 2014
Novel inhibitors of the MDM2-p53 interaction featuring hydrogen bond acceptors as carboxylic acid isosteresAna Z Gonzalez, Zhihong Li, Hilary P Beck, et al.
Pageof 3