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The Journal of Organic Chemistry
|
May 7, 2016
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production
Michal M Achmatowicz, John G Allen, Matthew M Bio, et al.
Chemical Research in Toxicology
|
January 26, 2010
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screening
Raju Subramanian, Matthew R Lee, John G Allen, et al.
Journal of Medicinal Chemistry
|
November 21, 2023
Imidazolone as an Amide Bioisostere in the Development of β-1,3-<i>N</i>-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors
Jeffrey J Jackson, Aaron C Siegmund, Wen-Ju Bai, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2013
The optimization of aminooxadiazoles as orally active inhibitors of Cdc7
Paul E Harrington, Matthew P Bourbeau, Christopher Fotsch, et al.
ACS Chemical Biology
|
July 20, 2016
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase
John G Allen, Mirna Mujacic, Michael J Frohn, et al.
Journal of Medicinal Chemistry
|
October 28, 2009
Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction
John G Allen, Matthew P Bourbeau, G Erich Wohlhieter, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancer
Qingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry
|
July 14, 2026
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS Inhibitors
Ryan P Wurz, Jennifer R Allen, John G Allen, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
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Search research articles
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Showing results (11-20 of 19) with videos related to
Sort By:
Page
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You have reached the last page of results.
This site can display upto 19 results.
The Journal of Organic Chemistry
|
May 7, 2016
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production
Michal M Achmatowicz, John G Allen, Matthew M Bio, et al.
Chemical Research in Toxicology
|
January 26, 2010
Cytochrome P450-mediated epoxidation of 2-aminothiazole-based AKT inhibitors: identification of novel GSH adducts and reduction of metabolic activation through structural changes guided by in silico and in vitro screening
Raju Subramanian, Matthew R Lee, John G Allen, et al.
Journal of Medicinal Chemistry
|
November 21, 2023
Imidazolone as an Amide Bioisostere in the Development of β-1,3-<i>N</i>-Acetylglucosaminyltransferase 2 (B3GNT2) Inhibitors
Jeffrey J Jackson, Aaron C Siegmund, Wen-Ju Bai, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 15, 2013
The optimization of aminooxadiazoles as orally active inhibitors of Cdc7
Paul E Harrington, Matthew P Bourbeau, Christopher Fotsch, et al.
ACS Chemical Biology
|
July 20, 2016
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-Dehydratase
John G Allen, Mirna Mujacic, Michael J Frohn, et al.
Journal of Medicinal Chemistry
|
October 28, 2009
Discovery and optimization of chromenotriazolopyrimidines as potent inhibitors of the mouse double minute 2-tumor protein 53 protein-protein interaction
John G Allen, Matthew P Bourbeau, G Erich Wohlhieter, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancer
Qingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry
|
July 14, 2026
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS Inhibitors
Ryan P Wurz, Jennifer R Allen, John G Allen, et al.
Journal of Medicinal Chemistry
|
December 11, 2019
Discovery of a Covalent Inhibitor of KRAS<sup>G12C</sup> (AMG 510) for the Treatment of Solid Tumors
Brian A Lanman, Jennifer R Allen, John G Allen, et al.
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of 2