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Biochemical and Biophysical Research Communications|February 24, 2007
The yeast Pdr5p multidrug transporter: how does it recognize so many substrates?John Golin, Suresh V Ambudkar, Leopold May
The Biochemical Journal|April 18, 2015
The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transportersJohn Golin, Suresh V Ambudkar
Biochemistry|July 13, 2005
The role of hydrogen bond acceptor groups in the interaction of substrates with Pdr5p, a major yeast drug transporterLeanne Hanson, Leopold May, Pamela Tuma, et al.
The Journal of Biological Chemistry|December 24, 2002
Studies with novel Pdr5p substrates demonstrate a strong size dependence for xenobiotic effluxJohn Golin, Suresh V Ambudkar, Michael M Gottesman, et al.
The Journal of Biological Chemistry|October 10, 2008
Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transportZuben E Sauna, Sherry Supernavage Bohn, Robert Rutledge, et al.
Molecular Microbiology|July 12, 2019
An A666G mutation in transmembrane helix 5 of the yeast multidrug transporter Pdr5 increases drug efflux by enhancing cooperativity between transport sitesNidhi Arya, Hadiar Rahman, Andrew Rudrow, et al.
The Journal of Biological Chemistry|August 13, 2014
Evidence for a molecular diode-based mechanism in a multispecific ATP-binding cassette (ABC) exporter: SER-1368 as a gatekeeping residue in the yeast multidrug transporter Pdr5Jitender Mehla, Robert Ernst, Rachel Moore, et al.
The Journal of Biological Chemistry|September 11, 2013
The deviant ATP-binding site of the multidrug efflux pump Pdr5 plays an active role in the transport cycleChristopher Furman, Jitender Mehla, Neeti Ananthaswamy, et al.
Biochemistry|April 30, 2010
The signaling interface of the yeast multidrug transporter Pdr5 adopts a cis conformation, and there are functional overlap and equivalence of the deviant and canonical Q-loop residuesNeeti Ananthaswamy, Robert Rutledge, Zuben E Sauna, et al.
Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy|October 5, 2023
Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1)Megumi Murakami, Andaleeb Sajid, Sabrina Lusvarghi, et al.
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