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Future Medicinal Chemistry
|
July 18, 2013
A fresh start in the hunt for novel antibacterials
John I Manchester
Methods in Molecular Biology (Clifton, N.J.)
|
October 3, 2002
Designing combinatorial libraries for efficient screening
John I Manchester, David S Hartsough
ACS Infectious Diseases
|
September 14, 2016
A New-Class Antibacterial-Almost. Lessons in Drug Discovery and Development: A Critical Analysis of More than 50 Years of Effort toward ATPase Inhibitors of DNA Gyrase and Topoisomerase IV
Gregory S Bisacchi, John I Manchester
Journal of Medicinal Chemistry
|
January 10, 2012
Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery
John I Manchester, Ed T Buurman, Gregory S Bisacchi, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Antimicrobial Activity of Adenine-Based Inhibitors of NAD(+)-Dependent DNA Ligase
Ed T Buurman, Valerie A Laganas, Ce Feng Liu, et al.
Nature Reviews. Drug Discovery
|
July 4, 2015
ESKAPEing the labyrinth of antibacterial discovery
Ruben Tommasi, Dean G Brown, Grant K Walkup, et al.
Archives of Biochemistry and Biophysics
|
February 8, 2002
Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol
Kevin J French, Dan A Rock, Denise A Rock, et al.
International Journal of Antimicrobial Agents
|
January 12, 2013
Novel topoisomerase inhibitors: microbiological characterisation and in vivo efficacy of pyrimidines
Maria Uria-Nickelsen, Georg Neckermann, Shubha Sriram, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 21, 2012
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV
John I Manchester, Daemian D Dussault, Jonathan A Rose, et al.
Journal of Medicinal Chemistry
|
October 9, 2013
Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents
Gregory S Basarab, John I Manchester, Shanta Bist, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 12) with videos related to
Sort By:
Page
of 2
Future Medicinal Chemistry
|
July 18, 2013
A fresh start in the hunt for novel antibacterials
John I Manchester
Methods in Molecular Biology (Clifton, N.J.)
|
October 3, 2002
Designing combinatorial libraries for efficient screening
John I Manchester, David S Hartsough
ACS Infectious Diseases
|
September 14, 2016
A New-Class Antibacterial-Almost. Lessons in Drug Discovery and Development: A Critical Analysis of More than 50 Years of Effort toward ATPase Inhibitors of DNA Gyrase and Topoisomerase IV
Gregory S Bisacchi, John I Manchester
Journal of Medicinal Chemistry
|
January 10, 2012
Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery
John I Manchester, Ed T Buurman, Gregory S Bisacchi, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Antimicrobial Activity of Adenine-Based Inhibitors of NAD(+)-Dependent DNA Ligase
Ed T Buurman, Valerie A Laganas, Ce Feng Liu, et al.
Nature Reviews. Drug Discovery
|
July 4, 2015
ESKAPEing the labyrinth of antibacterial discovery
Ruben Tommasi, Dean G Brown, Grant K Walkup, et al.
Archives of Biochemistry and Biophysics
|
February 8, 2002
Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol
Kevin J French, Dan A Rock, Denise A Rock, et al.
International Journal of Antimicrobial Agents
|
January 12, 2013
Novel topoisomerase inhibitors: microbiological characterisation and in vivo efficacy of pyrimidines
Maria Uria-Nickelsen, Georg Neckermann, Shubha Sriram, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 21, 2012
Discovery of a novel azaindole class of antibacterial agents targeting the ATPase domains of DNA gyrase and Topoisomerase IV
John I Manchester, Daemian D Dussault, Jonathan A Rose, et al.
Journal of Medicinal Chemistry
|
October 9, 2013
Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents
Gregory S Basarab, John I Manchester, Shanta Bist, et al.
Page
of 2