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Journal of Medicinal Chemistry
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June 8, 2010
Scaffold explorer: an interactive tool for organizing and mining structure-activity data spanning multiple chemotypes
Dimitris K Agrafiotis, John J M Wiener
Current Topics in Medicinal Chemistry
|
March 27, 2010
Recent advances in the design of cathepsin S inhibitors
John J M Wiener, Siquan Sun, Robin L Thurmond
Journal of Chemical Information and Modeling
|
April 21, 2011
Single R-Group Polymorphisms (SRPs) and R-cliffs: an intuitive framework for analyzing and visualizing activity cliffs in a single analog series
Dimitris K Agrafiotis, John J M Wiener, Andrew Skalkin, et al.
Angewandte Chemie (International Ed. in English)
|
April 3, 2008
Total synthesis and structural revision of callipeltoside C
Joseph Carpenter, Alan B Northrup, deMichael Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2013
Pyrazole-based arylalkyne cathepsin S inhibitors. Part III: modification of P4 region
John J M Wiener, Alvah Tyson Wickboldt, Steven Nguyen, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 23, 2010
Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions
John J M Wiener, Alvah T Wickboldt, Danielle K Wiener, et al.
Journal of Chemical Information and Modeling
|
March 1, 2019
Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry
Kelly L Damm-Ganamet, Nidhi Arora, Stephane Becart, et al.
European Journal of Pharmacology
|
May 22, 2020
Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse
William A Eckert, John J M Wiener, Hui Cai, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 21, 2007
Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis
Laurent Gomez, Michael D Hack, Jiejun Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 27, 2007
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains
John J M Wiener, Laurent Gomez, Hariharan Venkatesan, et al.
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of 2
Search research articles
Search
Showing results (1-10 of 14) with videos related to
Sort By:
Page
of 2
Journal of Medicinal Chemistry
|
June 8, 2010
Scaffold explorer: an interactive tool for organizing and mining structure-activity data spanning multiple chemotypes
Dimitris K Agrafiotis, John J M Wiener
Current Topics in Medicinal Chemistry
|
March 27, 2010
Recent advances in the design of cathepsin S inhibitors
John J M Wiener, Siquan Sun, Robin L Thurmond
Journal of Chemical Information and Modeling
|
April 21, 2011
Single R-Group Polymorphisms (SRPs) and R-cliffs: an intuitive framework for analyzing and visualizing activity cliffs in a single analog series
Dimitris K Agrafiotis, John J M Wiener, Andrew Skalkin, et al.
Angewandte Chemie (International Ed. in English)
|
April 3, 2008
Total synthesis and structural revision of callipeltoside C
Joseph Carpenter, Alan B Northrup, deMichael Chung, et al.
Bioorganic & Medicinal Chemistry Letters
|
January 15, 2013
Pyrazole-based arylalkyne cathepsin S inhibitors. Part III: modification of P4 region
John J M Wiener, Alvah Tyson Wickboldt, Steven Nguyen, et al.
Bioorganic & Medicinal Chemistry Letters
|
February 23, 2010
Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors. Part 2: Modification of P3, P4, and P5 regions
John J M Wiener, Alvah T Wickboldt, Danielle K Wiener, et al.
Journal of Chemical Information and Modeling
|
March 1, 2019
Accelerating Lead Identification by High Throughput Virtual Screening: Prospective Case Studies from the Pharmaceutical Industry
Kelly L Damm-Ganamet, Nidhi Arora, Stephane Becart, et al.
European Journal of Pharmacology
|
May 22, 2020
Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse
William A Eckert, John J M Wiener, Hui Cai, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 21, 2007
Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis
Laurent Gomez, Michael D Hack, Jiejun Wu, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 27, 2007
Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains
John J M Wiener, Laurent Gomez, Hariharan Venkatesan, et al.
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of 2