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Journal of Alzheimer'S Disease : JAD|April 13, 2011
High throughput monitoring of amyloid-β(42) assembly into soluble oligomers achieved by sensitive conformation state-dependent immunoassaysWei-Qin Zhao, Dawn Toolan, Robert W Hepler, et al.Journal of Medicinal Chemistry|September 18, 2015
Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel SynthesisWilliam D Shipe, Steven S Sharik, James C Barrow, et al.Journal of Lipid Research|May 11, 2010
PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brainMali Liu, Guoxin Wu, Jennifer Baysarowich, et al.Sleep|April 19, 2017
Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and WakeElena V Nikonova, Jason DA Gilliland, Keith Q Tanis, et al.Bioorganic & Medicinal Chemistry Letters|July 10, 2010
Tricyclic imidazole antagonists of the Neuropeptide S ReceptorB Wesley Trotter, Kausik K Nanda, Peter J Manley, et al.The Journal of Pharmacology and Experimental Therapeutics|August 5, 2010
In vitro characterization of T-type calcium channel antagonist TTA-A2 and in vivo effects on arousal in miceRichard L Kraus, Yuxing Li, Yun Gregan, et al.Sleep|March 5, 2016
Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in MonkeysPamela L Tannenbaum, Spencer J Tye, Joanne Stevens, et al.Bioorganic & Medicinal Chemistry Letters|March 9, 2010
Design and synthesis of conformationally constrained N,N-disubstituted 1,4-diazepanes as potent orexin receptor antagonistsPaul J Coleman, John D Schreier, Georgia B McGaughey, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|March 13, 2024
PET imaging of M4 muscarinic acetylcholine receptors in rhesus macaques using [11C]MK-6884: Quantification with kinetic modeling and receptor occupancy by CVL-231 (emraclidine), a novel positive allosteric modulatorVasily Belov, Nicolas J Guehl, Sridhar Duvvuri, et al.Nature Structural & Molecular Biology|March 8, 2016
Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptorsJie Yin, Kerim Babaoglu, Chad A Brautigam, et al.Pageof 12