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The Journal of Biological Chemistry|May 19, 2025
Biochemical impact of p300-mediated acetylation of replication protein A: Implications for DNA metabolic pathway choiceOnyekachi Ononye, Sneha Surendran, Tripthi Battapadi, et al.
Frontiers in Oncology|March 7, 2022
<i>In Vivo</i> Targeting Replication Protein A for Cancer TherapyPamela S VanderVere-Carozza, Navnath S Gavande, Shadia I Jalal, et al.
Cancers|October 16, 2024
Impact of Optimized Ku-DNA Binding Inhibitors on the Cellular and In Vivo DNA Damage ResponsePamela L Mendoza-Munoz, Narva Deshwar Kushwaha, Dineshsinha Chauhan, et al.
International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group|March 3, 2022
Characterization and initial demonstration of <i>in vivo</i> efficacy of a novel heat-activated metalloenediyne anti-cancer agentJoy Garrett, Erin Metzger, Mark W Dewhirst, et al.
RSC Medicinal Chemistry|September 24, 2025
Design, synthesis, and structure-activity relationship studies of 4-substituted phenylpyrazolidinone derivatives as potent Ku70/80 targeted DNA-PK inhibitorsNarva Deshwar Kushwaha, Pamela VanderVere-Carozza, Tyler L Vernon, et al.
Molecular Biosystems|January 10, 2014
Exploring a structural protein-drug interactome for new therapeutics in lung cancerXiaodong Peng, Fang Wang, Liwei Li, et al.
Nucleic Acids Research|October 29, 2020
Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku-DNA interactionNavnath S Gavande, Pamela S VanderVere-Carozza, Katherine S Pawelczak, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 16, 2014
The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizerFang Fang, Joanne Munck, Jessica Tang, et al.
Molecular Cell|July 3, 2021
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiencyKe Cong, Min Peng, Arne Nedergaard Kousholt, et al.
NAR Cancer|January 16, 2023
ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastropheJoshua R Heyza, Elmira Ekinci, Jacob Lindquist, et al.
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