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John M Pascal

Showing results (61-70 of 88) with videos related to

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Nature Communications|January 13, 2025
Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13Shang-Jung Cheng, Temitope Gafaar, Jijin R A Kuttiyatveetil, et al.
Molecular Cell|October 21, 2006
A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNAJohn M Pascal, Oleg V Tsodikov, Greg L Hura, et al.
Nucleic Acids Research|December 17, 2020
An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complexMichal Hammel, Ishtiaque Rashid, Aleksandr Sverzhinsky, et al.
Nature Communications|August 19, 2021
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylationYilun Sun, Jiji Chen, Shar-Yin N Huang, et al.
Journal of Medicinal Chemistry|June 13, 2014
Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitorsMaulik R Patel, Aaditya Bhatt, Jamin D Steffen, et al.
International Journal of Molecular Sciences|July 9, 2022
Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In VitroElena Y Kotova, Fu-Kai Hsieh, Han-Wen Chang, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 15, 2022
Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect CellsIshtiaque Rashid, Miaw-Sheue Tsai, Aleksandr Sverzhinsky, et al.
Journal of Medicinal Chemistry|May 3, 2019
Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and SelectivityUday Kiran Velagapudi, Marie-France Langelier, Cristina Delgado-Martin, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 28, 2011
Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticityTung O Chan, Jin Zhang, Ulrich Rodeck, et al.
Science Advances|April 29, 2026
PARP4 ADP-ribosylates PIDD1 to complete a phospho/SUMO/PAR-ylation cascade that orchestrates PIDDosome assemblyRicha B Shah, Yuanyuan Li, Ashley Person, et al.
Pageof 9

Showing results (61-70 of 88) with videos related to

Sort By:
Pageof 9
Nature Communications|January 13, 2025
Regulation of stress granule maturation and dynamics by poly(ADP-ribose) interaction with PARP13Shang-Jung Cheng, Temitope Gafaar, Jijin R A Kuttiyatveetil, et al.
Molecular Cell|October 21, 2006
A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNAJohn M Pascal, Oleg V Tsodikov, Greg L Hura, et al.
Nucleic Acids Research|December 17, 2020
An atypical BRCT-BRCT interaction with the XRCC1 scaffold protein compacts human DNA Ligase IIIα within a flexible DNA repair complexMichal Hammel, Ishtiaque Rashid, Aleksandr Sverzhinsky, et al.
Nature Communications|August 19, 2021
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylationYilun Sun, Jiji Chen, Shar-Yin N Huang, et al.
Journal of Medicinal Chemistry|June 13, 2014
Discovery and structure-activity relationship of novel 2,3-dihydrobenzofuran-7-carboxamide and 2,3-dihydrobenzofuran-3(2H)-one-7-carboxamide derivatives as poly(ADP-ribose)polymerase-1 inhibitorsMaulik R Patel, Aaditya Bhatt, Jamin D Steffen, et al.
International Journal of Molecular Sciences|July 9, 2022
Human PARP1 Facilitates Transcription through a Nucleosome and Histone Displacement by Pol II In VitroElena Y Kotova, Fu-Kai Hsieh, Han-Wen Chang, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 15, 2022
Purification and Characterization of Human DNA Ligase IIIα Complexes After Expression in Insect CellsIshtiaque Rashid, Miaw-Sheue Tsai, Aleksandr Sverzhinsky, et al.
Journal of Medicinal Chemistry|May 3, 2019
Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and SelectivityUday Kiran Velagapudi, Marie-France Langelier, Cristina Delgado-Martin, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 28, 2011
Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticityTung O Chan, Jin Zhang, Ulrich Rodeck, et al.
Science Advances|April 29, 2026
PARP4 ADP-ribosylates PIDD1 to complete a phospho/SUMO/PAR-ylation cascade that orchestrates PIDDosome assemblyRicha B Shah, Yuanyuan Li, Ashley Person, et al.
Pageof 9