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John M Sanders

Showing results (41-50 of 54) with videos related to

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Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Bioorganic & Medicinal Chemistry Letters|April 24, 2016
Potent, selective and orally bioavailable leucine-rich repeat kinase 2 (LRRK2) inhibitorsThomas J Greshock, John M Sanders, Robert E Drolet, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead effortsEdward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
Journal of Medicinal Chemistry|April 15, 2005
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorptionJohn M Sanders, Yongcheng Song, Julian M W Chan, et al.
ACS Medicinal Chemistry Letters|March 28, 2015
Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT)Scott T Harrison, Michael S Poslusney, James J Mulhearn, et al.
Chemmedchem|March 29, 2019
Discovery, Optimization, and Biological Characterization of 2,3,6-Trisubstituted Pyridine-Containing M<sub>4</sub> Positive Allosteric ModulatorsJeffrey W Schubert, Scott T Harrison, James Mulhearn, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2017
Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIVJohn D Schreier, Mark W Embrey, Izzat T Raheem, et al.
Journal of Medicinal Chemistry|June 11, 2014
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic painShawn J Stachel, John M Sanders, Darrell A Henze, et al.
Chemmedchem|December 4, 2014
Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorptionAbbas M Walji, Rosa I Sanchez, Sophie-Dorothee Clas, et al.
ACS Chemical Neuroscience|August 4, 2012
Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substratesRonald G Robinson, Sean M Smith, Scott E Wolkenberg, et al.
Pageof 6

Showing results (41-50 of 54) with videos related to

Sort By:
Pageof 6
Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
Bioorganic & Medicinal Chemistry Letters|April 24, 2016
Potent, selective and orally bioavailable leucine-rich repeat kinase 2 (LRRK2) inhibitorsThomas J Greshock, John M Sanders, Robert E Drolet, et al.
Bioorganic & Medicinal Chemistry Letters|April 23, 2010
3-Aryl-5-phenoxymethyl-1,3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead effortsEdward J Brnardic, Mark E Fraley, Robert M Garbaccio, et al.
Journal of Medicinal Chemistry|April 15, 2005
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorptionJohn M Sanders, Yongcheng Song, Julian M W Chan, et al.
ACS Medicinal Chemistry Letters|March 28, 2015
Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT)Scott T Harrison, Michael S Poslusney, James J Mulhearn, et al.
Chemmedchem|March 29, 2019
Discovery, Optimization, and Biological Characterization of 2,3,6-Trisubstituted Pyridine-Containing M<sub>4</sub> Positive Allosteric ModulatorsJeffrey W Schubert, Scott T Harrison, James Mulhearn, et al.
Bioorganic & Medicinal Chemistry Letters|March 14, 2017
Discovery and optimization of 2-pyridinone aminal integrase strand transfer inhibitors for the treatment of HIVJohn D Schreier, Mark W Embrey, Izzat T Raheem, et al.
Journal of Medicinal Chemistry|June 11, 2014
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic painShawn J Stachel, John M Sanders, Darrell A Henze, et al.
Chemmedchem|December 4, 2014
Discovery of MK-8970: an acetal carbonate prodrug of raltegravir with enhanced colonic absorptionAbbas M Walji, Rosa I Sanchez, Sophie-Dorothee Clas, et al.
ACS Chemical Neuroscience|August 4, 2012
Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substratesRonald G Robinson, Sean M Smith, Scott E Wolkenberg, et al.
Pageof 6