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ACS Infectious Diseases
|
December 12, 2018
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action
Malkeet Kumar, John Okombo, Dickson Mambwe, et al.
ACS Infectious Diseases
|
June 25, 2026
Using Unbiased Chemical Proteomics Approaches to Explore the Target Landscape of the Resistance Refractory 7-Azaindole MMV022224 in <i><i>Plasmodium falciparum</i></i>
Aisha J Syed, Rachel Milne, Victoriano Corpas-Lopez, et al.
Nature
|
November 29, 2019
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT
Jonathan Kim, Yong Zi Tan, Kathryn J Wicht, et al.
Plos Pathogens
|
October 29, 2024
A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants
Letícia Tiburcio Ferreira, Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, et al.
Plos One
|
May 10, 2014
A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya
Jason P Wendler, John Okombo, Roberto Amato, et al.
Journal of Medicinal Chemistry
|
February 23, 2021
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in <i>Plasmodium falciparum</i>
Aloysus Lawong, Suraksha Gahalawat, John Okombo, et al.
Biorxiv : the Preprint Server for Biology
|
November 24, 2025
Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in <i>Plasmodium</i> HSP90 Inhibitors
Fu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.
Journal of Medicinal Chemistry
|
January 18, 2017
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model
Kawaljit Singh, John Okombo, Christel Brunschwig, et al.
ACS Infectious Diseases
|
September 15, 2021
Prioritization of Molecular Targets for Antimalarial Drug Discovery
Barbara Forte, Sabine Ottilie, Andrew Plater, et al.
Cell Reports
|
July 6, 2026
Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding site
Fu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.
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Search research articles
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Showing results (41-50 of 66) with videos related to
Sort By:
Page
of 7
ACS Infectious Diseases
|
December 12, 2018
Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action
Malkeet Kumar, John Okombo, Dickson Mambwe, et al.
ACS Infectious Diseases
|
June 25, 2026
Using Unbiased Chemical Proteomics Approaches to Explore the Target Landscape of the Resistance Refractory 7-Azaindole MMV022224 in <i><i>Plasmodium falciparum</i></i>
Aisha J Syed, Rachel Milne, Victoriano Corpas-Lopez, et al.
Nature
|
November 29, 2019
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT
Jonathan Kim, Yong Zi Tan, Kathryn J Wicht, et al.
Plos Pathogens
|
October 29, 2024
A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants
Letícia Tiburcio Ferreira, Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, et al.
Plos One
|
May 10, 2014
A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya
Jason P Wendler, John Okombo, Roberto Amato, et al.
Journal of Medicinal Chemistry
|
February 23, 2021
Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in <i>Plasmodium falciparum</i>
Aloysus Lawong, Suraksha Gahalawat, John Okombo, et al.
Biorxiv : the Preprint Server for Biology
|
November 24, 2025
Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in <i>Plasmodium</i> HSP90 Inhibitors
Fu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.
Journal of Medicinal Chemistry
|
January 18, 2017
Antimalarial Pyrido[1,2-a]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model
Kawaljit Singh, John Okombo, Christel Brunschwig, et al.
ACS Infectious Diseases
|
September 15, 2021
Prioritization of Molecular Targets for Antimalarial Drug Discovery
Barbara Forte, Sabine Ottilie, Andrew Plater, et al.
Cell Reports
|
July 6, 2026
Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding site
Fu-Hsuan Ko, Amanda K Lukens, Mariana Laureano de Souza, et al.
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of 7