Showing results (1-10 of 38) with videos related to
Sort By:
Pageof 4
The AAPS Journal|October 23, 2010
Prediction of exposure-response relationships to support first-in-human study designJohn P GibbsEnvironmental Health Perspectives|August 5, 2005
Benchmark calculations for perchlorate from three human cohortsKenny S Crump, John P GibbsClinical Pharmacology and Therapeutics|November 7, 2017
Bedside to Bench: Integrating Quantitative Clinical Pharmacology and Reverse Translation to Optimize Drug DevelopmentJohn P Gibbs, Rajeev Menon, Sreeneeranj KasichayanulaDrug Metabolism and Disposition: the Biological Fate of Chemicals|June 10, 2006
Minimizing polymorphic metabolism in drug discovery: evaluation of the utility of in vitro methods for predicting pharmacokinetic consequences associated with CYP2D6 metabolismJohn P Gibbs, Ruth Hyland, Kuresh YoudimCombinatorial Chemistry & High Throughput Screening|January 8, 2010
Application of in vivo animal models to characterize the pharmacokinetic and pharmacodynamic properties of drug candidates in discovery settingsBenny M Amore, John P Gibbs, Maurice G EmeryClinical Pharmacokinetics|November 13, 2019
Quantitative Assessment of Elagolix Enzyme-Transporter Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic ModelingManoj S Chiney, Juki Ng, John P Gibbs, et al.Epilepsy Research|April 7, 2004
Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transportJohn P Gibbs, Moji Christianah Adeyeye, Ziping Yang, et al.Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 27, 2011
Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222Robert J Greene, Hua Tu, John P Gibbs, et al.Journal of Clinical Pharmacology|November 18, 2020
Informing Development of Bispecific Antibodies Using Physiologically Based Pharmacokinetic-Pharmacodynamic Models: Current Capabilities and Future OpportunitiesJohn P Gibbs, Theresa Yuraszeck, Carla Biesdorf, et al.Clinical and Translational Science|October 19, 2020
Mechanistic Modeling of Intra-Tumor Spatial Distribution of Antibody-Drug Conjugates: Insights into Dosing Strategies in OncologyJared Weddell, Manoj S Chiney, Sumit Bhatnagar, et al.Pageof 4