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Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 9, 2006
Evaluation of cerebrospinal fluid concentration and plasma free concentration as a surrogate measurement for brain free concentrationXingrong Liu, Bill J Smith, Cuiping Chen, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 4, 2005
Use of a physiologically based pharmacokinetic model to study the time to reach brain equilibrium: an experimental analysis of the role of blood-brain barrier permeability, plasma protein binding, and brain tissue bindingXingrong Liu, Bill J Smith, Cuiping Chen, et al.
Journal of the American College of Cardiology|October 23, 2012
Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statinsClapton S Dias, Adam J Shaywitz, Scott M Wasserman, et al.
Arthritis and Rheumatism|July 13, 2002
Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritisTino Munster, John P Gibbs, Danny Shen, et al.
Cancer Research Communications|October 24, 2025
A First-In-Human Study of the SUMOylation Inhibitor Subasumstat in Patients with Advanced/Metastatic Solid Tumors or Relapsed/Refractory Hematologic MalignanciesDejan Juric, Daniel Anderson, Afshin Dowlati, et al.
Cancer Research Communications|November 26, 2025
Phase 1b Study of Dazostinag plus Pembrolizumab after Hypofractionated Radiotherapy in Patients with Select Advanced Solid TumorsBenjamin T Cooper, Wade T Iams, David B Page, et al.
Clinical Pharmacology and Therapeutics|July 21, 2020
Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development ParadigmVijayalakshmi Chelliah, Georgia Lazarou, Sumit Bhatnagar, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 27, 2004
The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse modelAngela Doran, R Scott Obach, Bill J Smith, et al.
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