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John Parrington

Showing results (71-80 of 89) with videos related to

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Development (Cambridge, England)|July 12, 2017
PLCζ is the physiological trigger of the Ca<sup>2+</sup> oscillations that induce embryogenesis in mammals but conception can occur in its absenceAlaa Hachem, Jonathan Godwin, Margarida Ruas, et al.
The Journal of Biological Chemistry|August 20, 2010
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+Samantha J Pitt, Tim M Funnell, Mano Sitsapesan, et al.
The Journal of Biological Chemistry|December 7, 2014
Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signalingPei-Hui Lin, Pu Duann, Shinji Komazaki, et al.
Human Reproduction (Oxford, England)|November 19, 2011
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertilityJunaid Kashir, Michalis Konstantinidis, Celine Jones, et al.
The Journal of Clinical Investigation|October 18, 2008
Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo developmentSook-Young Yoon, Teru Jellerette, Ana Maria Salicioni, et al.
Human Reproduction (Oxford, England)|October 20, 2011
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytesJunaid Kashir, Celine Jones, Hoi Chang Lee, et al.
The Journal of Biological Chemistry|May 26, 2017
Synthesis of the Ca<sup>2+</sup>-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signalingWee K Lin, Emma L Bolton, Wilian A Cortopassi, et al.
Current Biology : CB|November 27, 2012
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killingLianne C Davis, Anthony J Morgan, Ji-Li Chen, et al.
Endocrinology|December 30, 2014
Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissuePamela V Lear, David González-Touceda, Begoña Porteiro Couto, et al.
The EMBO Journal|April 16, 2015
Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cellsMargarida Ruas, Lianne C Davis, Cheng-Chang Chen, et al.
Pageof 9

Showing results (71-80 of 89) with videos related to

Sort By:
Pageof 9
Development (Cambridge, England)|July 12, 2017
PLCζ is the physiological trigger of the Ca<sup>2+</sup> oscillations that induce embryogenesis in mammals but conception can occur in its absenceAlaa Hachem, Jonathan Godwin, Margarida Ruas, et al.
The Journal of Biological Chemistry|August 20, 2010
TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+Samantha J Pitt, Tim M Funnell, Mano Sitsapesan, et al.
The Journal of Biological Chemistry|December 7, 2014
Lysosomal two-pore channel subtype 2 (TPC2) regulates skeletal muscle autophagic signalingPei-Hui Lin, Pu Duann, Shinji Komazaki, et al.
Human Reproduction (Oxford, England)|November 19, 2011
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertilityJunaid Kashir, Michalis Konstantinidis, Celine Jones, et al.
The Journal of Clinical Investigation|October 18, 2008
Human sperm devoid of PLC, zeta 1 fail to induce Ca(2+) release and are unable to initiate the first step of embryo developmentSook-Young Yoon, Teru Jellerette, Ana Maria Salicioni, et al.
Human Reproduction (Oxford, England)|October 20, 2011
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytesJunaid Kashir, Celine Jones, Hoi Chang Lee, et al.
The Journal of Biological Chemistry|May 26, 2017
Synthesis of the Ca<sup>2+</sup>-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signalingWee K Lin, Emma L Bolton, Wilian A Cortopassi, et al.
Current Biology : CB|November 27, 2012
NAADP activates two-pore channels on T cell cytolytic granules to stimulate exocytosis and killingLianne C Davis, Anthony J Morgan, Ji-Li Chen, et al.
Endocrinology|December 30, 2014
Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissuePamela V Lear, David González-Touceda, Begoña Porteiro Couto, et al.
The EMBO Journal|April 16, 2015
Expression of Ca²⁺-permeable two-pore channels rescues NAADP signalling in TPC-deficient cellsMargarida Ruas, Lianne C Davis, Cheng-Chang Chen, et al.
Pageof 9