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John R Atack

Showing results (41-50 of 97) with videos related to

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British Journal of Pharmacology|May 9, 2009
The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primatesJohn R Atack, Wai-Si Eng, Ray E Gibson, et al.
Neuropharmacology|October 27, 2009
Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): role of GABA(A) receptor subtypesStephanie C Licata, Donna M Platt, Daniela Rüedi-Bettschen, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 31, 2006
In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the ratJonathan D Best, Mark T Jay, Franklin Otu, et al.
British Journal of Anaesthesia|January 3, 2021
Inhibition of a tonic inhibitory conductance in mouse hippocampal neurones by negative allosteric modulators of α5 subunit-containing γ-aminobutyric acid type A receptors: implications for treating cognitive deficitsMarc A Manzo, Dian-Shi Wang, Winston W Li, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|January 11, 2013
Reinforcing effects of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced rhesus monkeysNina M Shinday, Eileen K Sawyer, Bradford D Fischer, et al.
British Journal of Pharmacology|January 19, 2005
Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptorsJohn R Atack, Peter H Hutson, Neil Collinson, et al.
Bioorganic & Medicinal Chemistry Letters|April 20, 2006
2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: functionally selective GABAA alpha3-subtype agonistsRobert W Carling, Michael G N Russell, Kevin W Moore, et al.
Bioorganic & Medicinal Chemistry Letters|September 13, 2005
Pyrazolopyridinones as functionally selective GABAA ligandsWesley P Blackaby, John R Atack, Frances Bromidge, et al.
Bioorganic & Medicinal Chemistry Letters|December 31, 2005
Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxietySimon C Goodacre, David J Hallett, Robert W Carling, et al.
Biomolecules|April 27, 2024
Neurosteroid Modulation of Synaptic and Extrasynaptic GABA<sub>A</sub> Receptors of the Mouse Nucleus AccumbensScott J Mitchell, Grant D Phillips, Becks Tench, et al.
Pageof 10

Showing results (41-50 of 97) with videos related to

Sort By:
Pageof 10
British Journal of Pharmacology|May 9, 2009
The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primatesJohn R Atack, Wai-Si Eng, Ray E Gibson, et al.
Neuropharmacology|October 27, 2009
Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): role of GABA(A) receptor subtypesStephanie C Licata, Donna M Platt, Daniela Rüedi-Bettschen, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 31, 2006
In vivo characterization of Abeta(40) changes in brain and cerebrospinal fluid using the novel gamma-secretase inhibitor N-[cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide (MRK-560) in the ratJonathan D Best, Mark T Jay, Franklin Otu, et al.
British Journal of Anaesthesia|January 3, 2021
Inhibition of a tonic inhibitory conductance in mouse hippocampal neurones by negative allosteric modulators of α5 subunit-containing γ-aminobutyric acid type A receptors: implications for treating cognitive deficitsMarc A Manzo, Dian-Shi Wang, Winston W Li, et al.
Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology|January 11, 2013
Reinforcing effects of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced rhesus monkeysNina M Shinday, Eileen K Sawyer, Bradford D Fischer, et al.
British Journal of Pharmacology|January 19, 2005
Anxiogenic properties of an inverse agonist selective for alpha3 subunit-containing GABA A receptorsJohn R Atack, Peter H Hutson, Neil Collinson, et al.
Bioorganic & Medicinal Chemistry Letters|April 20, 2006
2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: functionally selective GABAA alpha3-subtype agonistsRobert W Carling, Michael G N Russell, Kevin W Moore, et al.
Bioorganic & Medicinal Chemistry Letters|September 13, 2005
Pyrazolopyridinones as functionally selective GABAA ligandsWesley P Blackaby, John R Atack, Frances Bromidge, et al.
Bioorganic & Medicinal Chemistry Letters|December 31, 2005
Imidazo[1,2-a]pyrazin-8-ones, imidazo[1,2-d][1,2,4]triazin-8-ones and imidazo[2,1-f][1,2,4]triazin-8-ones as alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxietySimon C Goodacre, David J Hallett, Robert W Carling, et al.
Biomolecules|April 27, 2024
Neurosteroid Modulation of Synaptic and Extrasynaptic GABA<sub>A</sub> Receptors of the Mouse Nucleus AccumbensScott J Mitchell, Grant D Phillips, Becks Tench, et al.
Pageof 10